NCT01484808

Brief Summary

This is a review of previously published data from a large prostate cancer prevention study known as REDUCE. It is the investigators intention to review whether prostate specific antigen (PSA) velocity (change over time) will predict the presence of prostate cancer and its grade and stage (severity).

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
6,600

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2012

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 30, 2011

Completed
2 days until next milestone

First Posted

Study publicly available on registry

December 2, 2011

Completed
1 month until next milestone

Study Start

First participant enrolled

January 1, 2012

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2012

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2012

Completed
Last Updated

December 2, 2011

Status Verified

November 1, 2011

Enrollment Period

3 months

First QC Date

November 30, 2011

Last Update Submit

December 1, 2011

Conditions

Keywords

PSA DensityProstate CancerProstate BiopsyPSA

Eligibility Criteria

Age50 Years - 74 Years
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Men with PSA elevation (\>=4), 50-74 years old with negative biopsy of the prostate at study entry

You may qualify if:

  • Men,
  • years old with elevated PSA (\>=4) along with negative entry biopsy of the prostate who had a subsequent biopsy by 24 months.

You may not qualify if:

  • Any positive biopsy of the prostate indicative of cancer upon entry

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Division of Urology, Brown University

Providence, Rhode Island, 02903, United States

Location

MeSH Terms

Conditions

Prostatic Neoplasms

Condition Hierarchy (Ancestors)

Genital Neoplasms, MaleUrogenital NeoplasmsNeoplasms by SiteNeoplasmsGenital Diseases, MaleGenital DiseasesUrogenital DiseasesProstatic DiseasesMale Urogenital Diseases

Study Officials

  • Steven I Cohen, MD

    University Urological Associates Inc.

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Steven I Cohen, MD

CONTACT

Samuel Elsamra, MD

CONTACT

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 30, 2011

First Posted

December 2, 2011

Study Start

January 1, 2012

Primary Completion

April 1, 2012

Study Completion

May 1, 2012

Last Updated

December 2, 2011

Record last verified: 2011-11

Locations