Prediction of Intraoperative Blood Loss and Postoperative Recovery by Liver Stiffness Measurement (Fibroscan®) in Right Hepatectomy

NCT01483859 | Completed DMC

• 1 other identifier: 1-2011-0053
• Study Type: interventional
• Target: 45
• Locations: 1 country
• Sites: 2

Brief Summary

Liver stiffness measurement (LSM) using Fibroscan®(EchoSens, Paris, France) is a newly introduced noninvasive tool that generates an elastic wave using a vibrator applied to the thoracic wall at the level of the right lobe of the liver and measures the prolongation velocity of the wave, which is directly associated with liver stiffness (LS). Although recent advances in surgical techniques and perioperative management have made with established perioperative management have now made it possible to perform hepatectomies as a safe procedure with minimum mortality, the possibility of massive blood loss and resultant transfusion during hepatectomy still exist. The objective of this research was to identify the role of liver stiffness measurement for the prediction of intraoperative blood loss and postoperative recovery after elective right hepatectomy.

Conditions

Liver Malignancy

Outcome Measures

Primary Outcomes (1)

• The correlation between the value of liver stiffness measurement and intraoperative blood loss during right hepatectomy

  The investigators will investigate the value of liver stiffness measurement and intraoperative blood loss during right hepatectomy through chart review. The investigators will analyze the correlation between the value of liver stiffness measurement and intraoperative blood loss during right hepatectomy

  Participants will be followed for perioperative period, approximate 6 weeks through chart review.

Study Arms (1)

right hepatectomy with preoperative LSM

OTHER

patients undergoing right hepatectomy with preoperative LSM between August 2007 and July 2011

Other: preoperative liver stiffness measurement

Interventions

preoperative liver stiffness measurement OTHER

Liver stiffness measurement (LSM) using Fibroscan is a newly introduced noninvasive tool that generates an elastic wave using a vibrator applied to the thoracic wall at the level of the right lobe of the liver and measures the prolongation velocity of the wave, which is directly associated with liver stiffness (LS).

Also known as: Liver stiffness measurement (LSM) using Fibroscan®(EchoSens, Paris, France)

right hepatectomy with preoperative LSM

Eligibility Criteria

• Age: 20 Years - 80 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• patients undergoing right hepatectomy between August 2007 and July 2011

You may not qualify if:

• patients undergoing right hepatectomy without preoperative liver stiffness measurement

Sponsors & Collaborators

• Yonsei University: lead

Study Sites (2)

Severance Hospital

Seoul, Seoul, 120-752, South Korea

Location

Severance Hospital

Seoul, South Korea

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: November 24, 2011
• First Posted: December 1, 2011
• Study Start: September 1, 2011
• Primary Completion: December 1, 2011
• Study Completion: December 1, 2012
• Last Updated: July 16, 2015

Record last verified: 2015-07

Locations

KR (2)