Evaluation of a Systematic Approach to Weaning From Mechanical Ventilation
Implantation of a Multidisciplinary Ventilator-weaning Protocol in a Intensive Care Unit of Teaching Hospital of Federal University of Uberlandia
1 other identifier
interventional
235
1 country
1
Brief Summary
Prolongation of mechanical ventilation poses serious personal and financial threats to healthcare consumers. The investigators objectives are create and implement an multidisciplinary evidenced-based ventilator-weaning protocol to assess whether a systematic approach compared with the physician's judgment only decreases time spent on the ventilator, complications of mechanical ventilation and length of stay in critical care unit.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Jan 2011
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2011
CompletedFirst Submitted
Initial submission to the registry
November 27, 2011
CompletedFirst Posted
Study publicly available on registry
November 30, 2011
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 1, 2012
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2012
CompletedResults Posted
Study results publicly available
March 4, 2013
CompletedMarch 4, 2013
January 1, 2013
1 year
November 27, 2011
January 12, 2013
January 27, 2013
Conditions
Keywords
Outcome Measures
Primary Outcomes (4)
Mortality
length of ICU stay (days)
Duration of Weaning From Mechanical Ventilation
days
Duration of Mechanical Ventilation
days
Length of Intensive Care Unit Stay
days
Study Arms (2)
Protocol-directed
EXPERIMENTALDiscontinuation of ventilation was based in multidisciplinary protocol.
Usual care
NO INTERVENTIONDiscontinuation of ventilation was left entirely to the discretion of the physicians.
Interventions
We implemented a multidisciplinary protocol for weaning from mechanical ventilation.This consist of a daily screening for readiness, performing a spontaneous breathing test, evaluation of signs of intolerance and decision on extubation.
Eligibility Criteria
You may qualify if:
- remain in mechanical ventilation for more than 24 hours
- begin weaning from mechanical ventilation
You may not qualify if:
- admitted in the unit already in weaning from mechanical ventilation
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Federal University of Uberlandia
Uberlândia, Minas Gerais, 38400-902, Brazil
Limitations and Caveats
The lack of sedation protocol in the intensive care unit.
Results Point of Contact
- Title
- Liliane Barbosa da Silva Passos
- Organization
- Federal University of Uberlândia
Study Officials
- PRINCIPAL INVESTIGATOR
Liliane Barbosa da Silva Passos
Federal University of Uberlandia
- STUDY CHAIR
Thulio Marquez Cunha
Federal University of Uberlandia
- STUDY CHAIR
Carlos Henrique Alves de Rezende, MD
Federal University of Uberlandia
Publication Agreements
- PI is Sponsor Employee
- Yes
- Restrictive Agreement
- No
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NON RANDOMIZED
- Masking
- NONE
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
November 27, 2011
First Posted
November 30, 2011
Study Start
January 1, 2011
Primary Completion
January 1, 2012
Study Completion
January 1, 2012
Last Updated
March 4, 2013
Results First Posted
March 4, 2013
Record last verified: 2013-01