NCT01480895

Brief Summary

Diabetes Mellitus (DM) is a chronic metabolic disorder with increasing incidence and long term complications. Its incidence differs in various ethnic populations.Gestational DM (GDM) is diagnosed when impaired glucose tolerance (IGT) is first detected during pregnancy. GDM incidence in Jewish and Bedouin women has been rising in recent years. It has been reported in many studies that women who had been diagnosed with GDM are more prone to GDM in their next pregnancies and to DM Type 2. Appropriate changes in everyday diet and physical exercise may reduce the chances for future GDM and type 2 DM. The investigators aim was to determine GDM frequency in the Negev area in Jewish and Bedouin populations and to construct a plan for follow up and reduce future problems by changing their life style.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
180

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Mar 2007

Typical duration for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2007

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2010

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2010

Completed
1.6 years until next milestone

First Submitted

Initial submission to the registry

November 22, 2011

Completed
7 days until next milestone

First Posted

Study publicly available on registry

November 29, 2011

Completed
Last Updated

November 29, 2011

Status Verified

November 1, 2011

Enrollment Period

3 years

First QC Date

November 22, 2011

Last Update Submit

November 28, 2011

Conditions

Keywords

Diabetes Mellitus Type 2Gestational Diabetes MellitusGlucose IntolerancePhysical exerciseNutritional HabitsDyslipidemia

Outcome Measures

Primary Outcomes (2)

  • Change in HOMA ratios (Homeostasis Model Assessments of Insulin Resistance).

    The metabolic parameters included glucose and insulin levels, to enable calculations of HOMA IR. (Homeostasis Model Assessment of Insulin Resistance).

    Determination of HOMA after one year.

  • Change in HOMA.

    HOMA calculations post partum.

    Detrmination of HOMA after two years.

Secondary Outcomes (4)

  • Determinations of blood lipids .

    Post partum lipids levels after one year.

  • Change in lipids levels after two years post partum.

    2 years after delivery.

  • Post partum BMI changes.

    one year after delivery.

  • BMI changes after delivery.

    Two years after delivery.

Study Arms (2)

Post GDM follow-up group.

NO INTERVENTION
Behavioral: Lifestyle instruction for Jews and Bedouin GDM women.

lifestyle intervention group.

EXPERIMENTAL

The women in this group had participated in lifestyle intervention by diet instructions and physical exercise program.

Behavioral: Lifestyle instruction for Jews and Bedouin GDM women.

Interventions

Every several months the women had instructions and checkups.

Also known as: Jew and Bedouin women with recent GDM in the Negev area.
Post GDM follow-up group.lifestyle intervention group.

Eligibility Criteria

Age18 Years - 43 Years
Sexfemale
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Diagnosis of gestational diabetes.

You may not qualify if:

  • Diabetes Mellitus

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Diabetes, GestationalDiabetes Mellitus, Type 2Glucose IntoleranceMotor ActivityDyslipidemias

Condition Hierarchy (Ancestors)

Pregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesDiabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesHyperglycemiaBehaviorLipid Metabolism Disorders

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr Naomi Meyerstein M D

Study Record Dates

First Submitted

November 22, 2011

First Posted

November 29, 2011

Study Start

March 1, 2007

Primary Completion

March 1, 2010

Study Completion

April 1, 2010

Last Updated

November 29, 2011

Record last verified: 2011-11