NCT01476917

Brief Summary

The Study is a multi-center, prospective, open label, single-arm, three-month, long-term study of the Attune Sleep Apnea System for the treatment of obstructive sleep apnea (OSA). The objective of the study is to monitor long-term use of the Attune Sleep Apnea System.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
39

participants targeted

Target at P25-P50 for phase_2

Timeline
Completed

Started Nov 2011

Shorter than P25 for phase_2

Geographic Reach
1 country

6 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2011

Completed
15 days until next milestone

First Submitted

Initial submission to the registry

November 16, 2011

Completed
6 days until next milestone

First Posted

Study publicly available on registry

November 22, 2011

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2012

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2012

Completed
Last Updated

November 7, 2012

Status Verified

November 1, 2012

Enrollment Period

7 months

First QC Date

November 16, 2011

Last Update Submit

November 5, 2012

Conditions

Outcome Measures

Primary Outcomes (1)

  • Mean number of hours per night of device use over a 3-month period

    Nightly use will be monitored over a 3-month take-home period.

    Each night's use

Study Arms (1)

Treatment

EXPERIMENTAL

Subjects that completed the ATLAST Study

Device: Attune Sleep Apnea System

Interventions

Observation of Attune Sleep Apnea System for use during sleep.

Treatment

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Subject participated in the ATLAST Study, and completed the 28-day take-home period
  • Subject understands the Study protocol and is willing and able to comply with Study requirements and sign the informed consent form.
  • The study physician and investigator believe that study participation is appropriate for the subject.
  • Subject has at least one molar in each of the four quadrants of the mouth (right upper, right lower, left upper, and left lower).

You may not qualify if:

  • Female subjects who are pregnant or intend to become pregnant during the study period.
  • Poor nasal patency as evidenced by the inability to breathe through the nose with the mouth closed.
  • Oral cavity infection or any other oral or dental condition or problem that would limit subject use of the Attune Sleep Apnea System
  • History of any OSA surgical treatment

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

REM Medical

Phoenix, Arizona, 85037, United States

Location

Penninsula Sleep Center (PSC)

Burlingame, California, 94010, United States

Location

SRI International

Menlo Park, California, 94025, United States

Location

Sleep Disorders Center of Georgia

Atlanta, Georgia, 30342, United States

Location

SleepMed

Columbia, South Carolina, 29201, United States

Location

Sleep Medicine Associates of Texas (SMAT)

Dallas, Texas, 75231, United States

Location

MeSH Terms

Conditions

Sleep Apnea, Obstructive

Condition Hierarchy (Ancestors)

Sleep Apnea SyndromesApneaRespiration DisordersRespiratory Tract DiseasesSleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System Diseases

Study Officials

  • Ian Colrain, PhD

    Stanford Research Institute (SRI)

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 16, 2011

First Posted

November 22, 2011

Study Start

November 1, 2011

Primary Completion

June 1, 2012

Study Completion

October 1, 2012

Last Updated

November 7, 2012

Record last verified: 2012-11

Locations