NCT01465698

Brief Summary

NURSE-RCT is a randomized controlled trial which aims at prevention of evolution of chronic low back pain (LBP) and related disability in female nurses. The study investigates the effectiveness and financial feasibility of six months neuromuscular training and counselling, and their combination on LBP, movement dysfunction and fear-avoidance behaviour. The target for neuromuscular training is to reduce movement dysfunction and motor control impairments, caused by trauma and subfailure injuries of spinal ligaments. Training aims at enhancement of motor control of lumbar neutral zone in different positions and movements, balance, coordination, trunk muscle endurance and leg strength. The target for counselling is change in attitudes and behaviour, which help to reduce the fear of pain and encourage to physical activity and other physical tasks. The hypothesis is that together neuromuscular exercise and counselling have a stronger influence on LBP, movement dysfunction and fear-avoidance behaviour than either used alone. Assessments of effectiveness will be conducted after six, 12, and 24 months of the beginning of interventions.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
219

participants targeted

Target at P75+ for not_applicable low-back-pain

Timeline
Completed

Started Nov 2011

Longer than P75 for not_applicable low-back-pain

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 28, 2011

Completed
4 days until next milestone

Study Start

First participant enrolled

November 1, 2011

Completed
6 days until next milestone

First Posted

Study publicly available on registry

November 7, 2011

Completed
4.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2016

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2016

Completed
Last Updated

January 22, 2016

Status Verified

January 1, 2016

Enrollment Period

4.2 years

First QC Date

October 28, 2011

Last Update Submit

January 21, 2016

Conditions

Keywords

exercisecounselingmovement controlfear avoidance

Outcome Measures

Primary Outcomes (1)

  • Intensity of LBP for past month assessed by Visual Analog Scale

    Changes in the intensity of LPB at the given time frame

    Baseline, 6, 12 and 24 months follow-up

Secondary Outcomes (3)

  • Movement control impairment

    Baseline, 6, 12 and 24 months follow-up

  • Fear-avoidance beliefs questionnaire

    Baseline, 6, 12 and 24 months follow-up

  • Objective assessment of physical activity with accelerometer

    Baseline, 6, 12 and 24 months follow-up

Study Arms (4)

Exercise

EXPERIMENTAL
Behavioral: Exercise

Counseling

EXPERIMENTAL
Behavioral: Counseling

Exercise and counseling

EXPERIMENTAL
Behavioral: Exercise and counseling

Control group

OTHER

Participants in the control group only participate in study measurements.

Other: Control group

Interventions

ExerciseBEHAVIORAL

The main target for exercise intervention is to restore impairments in movement control. First, the participants need to learn the proper technique of each exercise, second to achieve movement control of lumbar neutral zone in each exercise, and finally to increase the challenge of exercises for balance, coordination, muscular endurance and strength. Target dose for exercise is twice a week, 60 minutes per session for six months. The neuromuscular exercise program is progressive including three different performance levels. During the first eight weeks, the supervised exercise sessions will take place twice a week. The next 16 weeks the participants have one instructed weekly session, and they exercise once a week at home with help of a DVD or booklet produced for the study

Also known as: Neuromuscular exercise, Control of lumbar neutral zone, Physical fitness
Exercise
CounselingBEHAVIORAL

Counseling is conducted according cognitive-behavioral principles. Fear-avoidance model is implemented using problem based learning. The objective is to change participants' understanding of LBP towards less fearful and negative beliefs, and to provide encouragement for usual daily activities, including physical activity. Advice on nursing tasks that are strenuous for low back is aimed to improve awareness of injury risk and provide examples of proper postures and movements. The target is that participants in counseling groups attend 10 sessions each lasting 45 minutes. During the first four weeks the groups meet every second week, and after that once a month up to six months. Participants will receive workbooks to enhance problem-based learning.

Also known as: Behavioral counseling, Fear avoidance beliefs, Physical activity promotion
Counseling

Participants take part in both exercise and counseling as described in the separate interventions.

Also known as: Neuromuscular exercise, Control of lumbar neutral zone, Physical fitness, Behavioral counseling, Fear avoidance beliefs, Physical activity promotion
Exercise and counseling

Participants in the control group take part only in measurements of NURSE-RCT.

Also known as: No intervention
Control group

Eligibility Criteria

Age40 Years - 55 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • woman aged 40 to 55
  • working at one's current nursing job at least for 12 months
  • intensity of LBP on Visual Analog Scale (VAS) has been greater than 20mm (scale 0-100) during the last month

You may not qualify if:

  • serious former back injury (fracture, surgery, discus prolapse)
  • chronic low back symptoms i.e. time when last experienced no low back pain is longer than six months
  • pregnant or recent delivery (\<12months)
  • general health problems prevent moderate exercise
  • body mass index \>35

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

UKK Institute for Health Promotion Reserach

Tampere, 33500, Finland

Location

Related Publications (3)

  • Kolu P, Suni JH, Tokola K, Raitanen J, Rinne M, Taulaniemi A, Husu P, Kankaanpaa M, Parkkari J. Neuromuscular exercise and counseling for treating recurrent low back pain in female healthcare workers-Findings from a 24-month follow-up study of a randomized controlled trial. Scand J Med Sci Sports. 2023 Nov;33(11):2239-2249. doi: 10.1111/sms.14451. Epub 2023 Jul 19.

  • Suni JH, Virkkunen T, Husu P, Tokola K, Parkkari J, Kankaanpaa M. Reliability and construct validity of the modified Finnish version of the 9-item patient health questionnaire and its associations within the biopsychosocial framework among female health-care workers with sub-acute or recurrent low back pain. BMC Musculoskelet Disord. 2021 Jan 7;22(1):37. doi: 10.1186/s12891-020-03832-y.

  • Suni JH, Kolu P, Tokola K, Raitanen J, Rinne M, Taulaniemi A, Parkkari J, Kankaanpaa M. Effectiveness and cost-effectiveness of neuromuscular exercise and back care counseling in female healthcare workers with recurrent non-specific low back pain: a blinded four-arm randomized controlled trial. BMC Public Health. 2018 Dec 17;18(1):1376. doi: 10.1186/s12889-018-6293-9.

MeSH Terms

Conditions

Low Back PainMotor Activity

Interventions

ExerciseMuscle Stretching ExercisesPhysical FitnessCounselingBehavior TherapyControl Groups

Condition Hierarchy (Ancestors)

Back PainPainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsBehavior

Intervention Hierarchy (Ancestors)

Motor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological PhenomenaExercise TherapyRehabilitationAftercareContinuity of Patient CarePatient CareTherapeuticsPhysical Therapy ModalitiesHealthPopulation CharacteristicsMental Health ServicesBehavioral Disciplines and ActivitiesCommunity Health ServicesHealth ServicesHealth Care Facilities Workforce and ServicesPsychotherapyEpidemiologic Research DesignEpidemiologic MethodsInvestigative TechniquesResearch DesignMethods

Study Officials

  • Jaana H Suni, DSc, Docent

    UKK Institute

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Senior Reseracher

Study Record Dates

First Submitted

October 28, 2011

First Posted

November 7, 2011

Study Start

November 1, 2011

Primary Completion

January 1, 2016

Study Completion

January 1, 2016

Last Updated

January 22, 2016

Record last verified: 2016-01

Data Sharing

IPD Sharing
Will not share

Locations