NCT01465594

Brief Summary

The study aims to show the technical feasibility of the suprapubic urinary diversion after endoscopic extraperitoneal radical prostatectomy (EERPE) and has a greater comfort for the patients with at least the same catheter complication rate in comparison to the urethral urinary diversion.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
106

participants targeted

Target at P50-P75 for not_applicable pain

Timeline
Completed

Started Nov 2011

Longer than P75 for not_applicable pain

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2011

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

November 2, 2011

Completed
5 days until next milestone

First Posted

Study publicly available on registry

November 7, 2011

Completed
3.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2015

Completed
Last Updated

May 20, 2015

Status Verified

May 1, 2015

Enrollment Period

3.4 years

First QC Date

November 2, 2011

Last Update Submit

May 19, 2015

Conditions

Keywords

Pain Measurement

Outcome Measures

Primary Outcomes (1)

  • Superiority of suprapubic catheter after EERPE

    Superiority of suprapubic catheter versus transurethral catheter regarding QoL /Patient comfort

    2nd postoperative day

Secondary Outcomes (1)

  • Comparison of QoL in both arms measured by visual analogue (pain) scale

    1st and 3rd until 5th postoperative day

Study Arms (2)

transurethral catheter after EERPE/ RALP

ACTIVE COMPARATOR

Recording of QoL measured by visual analogue ( pain )scale,EORTC QlQ -C 30 and QLQ - PR 25 questionnaires, incontinence rate, complication rate regarding insufficiency and strictures of vesicourethral anastomoses and urinary tract infection; demand of re-catheterization due to urinary retention and demand of antispasmodics

Procedure: transurethral catheter after EERPE/ RALPProcedure: suprapubic catheter after EERPE /RALP

suprapubic catheter after EERPE /RALP

ACTIVE COMPARATOR

Recording of QoL measured by visual analogue ( pain )scale,EORTC QlQ -C 30 and QLQ - PR 25 questionnaires, incontinence rate, complication rate regarding insufficiency and strictures of vesicourethral anastomoses and urinary tract infection; demand of re-catheterization due to urinary retention and demand of antispasmodics

Procedure: transurethral catheter after EERPE/ RALPProcedure: suprapubic catheter after EERPE /RALP

Interventions

transurethral catheter after EERPE/ RALP

suprapubic catheter after EERPE /RALPtransurethral catheter after EERPE/ RALP

suprapubic catheter after EERPE /RALP

suprapubic catheter after EERPE /RALPtransurethral catheter after EERPE/ RALP

Eligibility Criteria

Age18 Years+
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adenocarcinoma of the prostate,
  • Subjects treated by conventional or robotic assisted laparoscopic prostatectomy
  • Be willing/able to adhere to follow up visits

You may not qualify if:

  • Subjects treated by retropubic or perineal prostatectomy Subjects with known bladder cancer
  • Contraindications for anticholinergic drugs
  • Waist measurement \> 100 cm
  • No written informed consent
  • Age \< 18 years
  • Subjects with known narrow-angle glaucoma

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital, Urological department

Düsseldorf, 40225, Germany

Location

MeSH Terms

Conditions

Pain

Condition Hierarchy (Ancestors)

Neurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Christian Arsov, Dr

    Heinrich Heine Universität

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 2, 2011

First Posted

November 7, 2011

Study Start

November 1, 2011

Primary Completion

April 1, 2015

Study Completion

April 1, 2015

Last Updated

May 20, 2015

Record last verified: 2015-05

Locations