NCT01463904

Brief Summary

Single-Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy is a modified and simplified duodenal switch. It is performed on morbid obese patients and severe T2DM patients with obesity, and a proper weight loss is expected as well as a decrease in the cardiac risk and a remission of T2DM. A lower complication rate than for duodenal switch is expected.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
250

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Apr 2007

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2007

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2009

Completed
2.3 years until next milestone

First Submitted

Initial submission to the registry

October 31, 2011

Completed
2 days until next milestone

First Posted

Study publicly available on registry

November 2, 2011

Completed
3.4 years until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2015

Completed
Last Updated

November 2, 2011

Status Verified

October 1, 2011

Enrollment Period

2.3 years

First QC Date

October 31, 2011

Last Update Submit

November 1, 2011

Conditions

Keywords

Morbid obesityduodenal switchdiabetesdecrease in cardiac riskremission of T2DM

Study Arms (1)

Morbid obese, diabetics

Patients with morbid obesity or severe metabolic disease

Procedure: SADI-S 250

Interventions

SADI-S 250PROCEDURE

Single-Anastomosis Duodeno-Ileal bypass with Sleeve gastrectomy

Morbid obese, diabetics

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Morbid obesity patients and patients with obesity and T2DM

You may qualify if:

  • BMI \> 30 with T2DM or BMI \> 40

You may not qualify if:

  • Oncologic patients, alcoholic patients, mentally retarded

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hospital Clínico San Carlos

Madrid, Madrid, 28040, Spain

RECRUITING

Biospecimen

Retention: SAMPLES WITH DNA

Samples of subcutaneous and visceral fat, and samples of liver tissue.

MeSH Terms

Conditions

Obesity, MorbidDiabetes Mellitus

Condition Hierarchy (Ancestors)

ObesityOverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and SymptomsGlucose Metabolism DisordersMetabolic DiseasesEndocrine System Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD, PhD

Study Record Dates

First Submitted

October 31, 2011

First Posted

November 2, 2011

Study Start

April 1, 2007

Primary Completion

July 1, 2009

Study Completion

April 1, 2015

Last Updated

November 2, 2011

Record last verified: 2011-10

Locations