Aortic Calcification - is it a Marker for Carotid Artery Stenosis?

NCT01458860 | Unknown

• 1 other identifier: ZIV-11-0041
• Study Type: observational
• Target: 200
• Locations: 0 countries
• Sites: N/A

Brief Summary

Atherosclerosis is the major contributor for the morbidity and mortality for the variety of cardiovascular diseases. Aortic calcification on x-ray is a marker for arterial atherosclerosis and an independent prognostic factor for the morbidity and mortality from a cardiovascular event. Carotid artery stenoses is the current accepted indication for interventional treatment of carotid artery, for the prevention of embolic event, while other arterial atherosclerosis indication, is for hemodynamic disturbance and ischemic outcome. This research will try to find whether incidental aortic calcification can predict carotid artery stenosis. Two groups will be chosen: group A - patients who had CT scan in the hospital (for different indications); Group B - patients (not from the first group) who have a significant carotid artery stenosis who are indicated for interventional treatment. The data to analyze: Group A - Patients with aortic calcification, carotid artery stenosis, and patients with both Group B - Patients who have aortic calcification Comparison of the populations within the group and among the two will show if a significant correlation between aortic calcification and carotid artery stenosis exist.

Conditions

Carotid Artery Stenosis; Aortic Calcification

Study Arms (2)

GROUP A

patients had a CT

GROUP B

patients with severe carotid artery stenosis

Eligibility Criteria

• Age: 40 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Group A - patients who had a CT scan Group B - patients who have severe carotid artery stenosis

You may qualify if:

• Group A - patients, age 40-99 years, that had a CT scan for any indication Group B - patients with severe carotid artery stenosis, that indicated for treatment

You may not qualify if:

• Group A - age \<40 years
• Group B - carotid artery stenosis, without intention-to-treat

Sponsors & Collaborators

• Ziv Hospital: lead

MeSH Terms

Conditions

Carotid Stenosis

Condition Hierarchy (Ancestors)

Carotid Artery Diseases; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Arterial Occlusive Diseases; Vascular Diseases; Cardiovascular Diseases

Study Officials

• Tal Salamon, MD

  Zim medical center

  PRINCIPAL INVESTIGATOR

• Alexander Altsuler, MD

  Ziv Medical Center

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: CASE CROSSOVER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 24, 2011
• First Posted: October 25, 2011
• Study Start: February 1, 2012
• Primary Completion: February 1, 2012
• Study Completion: February 1, 2014
• Last Updated: November 1, 2011

Record last verified: 2011-10