NCT01446029

Brief Summary

The purpose of this study is to determine if the adoption of a chronic care model in conjunction with tele monitoring and case management can reduce the risk of death, hospitalization, emergency room visits, or admission to a skilled nursing facility in patients with chronic kidney disease compared to usual care.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
601

participants targeted

Target at P75+ for phase_3

Timeline
Completed

Started Mar 2012

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 28, 2011

Completed
6 days until next milestone

First Posted

Study publicly available on registry

October 4, 2011

Completed
5 months until next milestone

Study Start

First participant enrolled

March 1, 2012

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2013

Completed
Last Updated

August 4, 2014

Status Verified

August 1, 2014

Enrollment Period

1.6 years

First QC Date

September 28, 2011

Last Update Submit

August 1, 2014

Conditions

Keywords

TelemonitoringChronic Kidney Disease

Outcome Measures

Primary Outcomes (1)

  • composite clinical outcome (reduce risk of death, hospitalization, emergency room visits, admission to skilled nursing facility)

    one year

Secondary Outcomes (4)

  • reduction of cost

    one year

  • incidence of end stage kidney disease

    one year

  • hospital re-admission

    one year

  • Intervention group achieving National Kidney guideline values for blood pressure, glycemia, lipids, and hemoglobin

    one year

Study Arms (2)

Usual Care

NO INTERVENTION

Intervention Device

ACTIVE COMPARATOR
Device: Video Telemonitoring Device with Clinical Care Modules

Interventions

Telemonitoring of vital signs; videoconferencing, remote titration of diabetes, blood pressure, and lipid medications using evidence based treatment algorithm, and cooperative goal setting using education modules to enhance lifestyle changes

Also known as: Telehealth, Telemonitoring, Chronic Disease Management
Intervention Device

Eligibility Criteria

Age18 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

VA Medical Center

Minneapolis, Minnesota, 55417, United States

Location

Related Publications (3)

  • Barrett BJ, Garg AX, Goeree R, Levin A, Molzahn A, Rigatto C, Singer J, Soltys G, Soroka S, Ayers D, Parfrey PS. A nurse-coordinated model of care versus usual care for stage 3/4 chronic kidney disease in the community: a randomized controlled trial. Clin J Am Soc Nephrol. 2011 Jun;6(6):1241-7. doi: 10.2215/CJN.07160810. Epub 2011 May 26.

    PMID: 21617090BACKGROUND
  • Ishani A, Greer N, Taylor BC, Kubes L, Cole P, Atwood M, Clothier B, Ercan-Fang N. Effect of nurse case management compared with usual care on controlling cardiovascular risk factors in patients with diabetes: a randomized controlled trial. Diabetes Care. 2011 Aug;34(8):1689-94. doi: 10.2337/dc10-2121. Epub 2011 Jun 2.

    PMID: 21636796BACKGROUND
  • Santschi V, Chiolero A, Burnand B, Colosimo AL, Paradis G. Impact of pharmacist care in the management of cardiovascular disease risk factors: a systematic review and meta-analysis of randomized trials. Arch Intern Med. 2011 Sep 12;171(16):1441-53. doi: 10.1001/archinternmed.2011.399.

    PMID: 21911628BACKGROUND

MeSH Terms

Conditions

Renal Insufficiency, Chronic

Condition Hierarchy (Ancestors)

Renal InsufficiencyKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Areef Ishani, MD

    US Department of Veterans Affairs

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
FED
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Chief, Section of Nephrology; Associate Professor of Medicine

Study Record Dates

First Submitted

September 28, 2011

First Posted

October 4, 2011

Study Start

March 1, 2012

Primary Completion

October 1, 2013

Study Completion

October 1, 2013

Last Updated

August 4, 2014

Record last verified: 2014-08

Locations