NCT01445249

Brief Summary

Forefoot surgery includes bunion surgery and similar reconstructive bone cutting surgery and is very painful. Local anaesthetic nerve blocks are used to provide pain relief after this work. The purpose of this study is to compare two techniques: one using anatomical landmarks alone to guide local anaesthetic infiltration, the other using peripheral nerve stimulation to guide local anaesthetic infiltration (termed medial forefoot block). The two techniques will be compared for reliability of postoperative analgesia.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
72

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Mar 2007

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2007

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2009

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2009

Completed
2.5 years until next milestone

First Submitted

Initial submission to the registry

August 17, 2011

Completed
2 months until next milestone

First Posted

Study publicly available on registry

October 3, 2011

Completed
Last Updated

July 15, 2019

Status Verified

July 1, 2019

Enrollment Period

2 years

First QC Date

August 17, 2011

Last Update Submit

July 11, 2019

Conditions

Keywords

regional anaesthetic techniquessurgery orthopaedic

Outcome Measures

Primary Outcomes (1)

  • Efficacy of local anaesthetic block.

    The number of patients in each study arm with altered sensation to cold and pin prick, together with no requirement for opiate analgesia, following surgery was recorded.

    Over ninety minutes from the start of the study.

Secondary Outcomes (1)

  • Intravenous opiate usage following surgery

    24 hours following surgery

Study Arms (2)

Landmark guided ankle block

ACTIVE COMPARATOR

This group will receive a landmark guided ankle block.

Procedure: Landmark guided ankle block.

This group will be given a PNS guided ankle block

ACTIVE COMPARATOR

Peripheral nerve stimulation will be used in this group to guide local anaesthetic infiltration. The technique is termed medial forefoot block.

Procedure: PNS guided block.

Interventions

25-30mls 0.5% levobupivacaine will be infiltrated to provide a landmark guided ankle block.

Also known as: Other names not required
Landmark guided ankle block

This group will have 25-30mls of 0.5% levobupivacaine infiltrated as directed by peripheral nerve stimulation.

Also known as: Other names not required
This group will be given a PNS guided ankle block

Eligibility Criteria

Age18 Years - 85 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Fit adults requiring forefoot surgery with bone cutting

You may not qualify if:

  • Morbid obesity (BMI \> 40)
  • Known contraindications to regional anaesthesia

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Castle Hill Hospital. Castle Road, Cottingham,

Hull, East Yorkshire, HU16 5JQ, United Kingdom

Location

MeSH Terms

Conditions

Hallux Valgus

Condition Hierarchy (Ancestors)

Foot DeformitiesMusculoskeletal Diseases

Study Officials

  • Andrew J Coe, MbChB FRCA

    Hull and East Yorks NHS Trust

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 17, 2011

First Posted

October 3, 2011

Study Start

March 1, 2007

Primary Completion

March 1, 2009

Study Completion

March 1, 2009

Last Updated

July 15, 2019

Record last verified: 2019-07

Locations