Touch and Attention MRI Study

NCT01432288 | Completed DMC

• 1 other identifier: WFUIRB00016834
• Study Type: observational
• Target: 10
• Locations: 1 country
• Sites: 1

Brief Summary

This study will measure resting state network central nervous system activity by functional magnetic resonance imaging (fMRI) during 4 separate interactions with a clinician. 1. Hypothesis 1. Because they are different sensory systems, there will be different patterns of Mirror Neuron System (MNS)and Resting State Network (RSN) Central Nervous System (CNS) activity for visual vs. tactile stimulation, regardless of Loving Kindness Meditation (LKM). Hypothesis 2. Because of unconscious, non-verbal signals, such as the practitioner's facial expression and respiratory rate, subjects' patterns of MNS and RSN CNS activity will differ for LKM+ vs. LKM- stimulation for both visual and tactile interventions. Hypothesis 3. Because there is greater opportunity to detect signals from two sensory systems than one, the differences between CNS MNS and RSN activity patterns for LKM+ and LKM- will be greater for combined visual + tactile than for either visual or tactile stimulation alone.

Conditions

Central Nervous System

Eligibility Criteria

• Age: 18 Years - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Participants will be healthy individuals, 18\< 40 years old, and can understand and respond to verbal directions while in an fMRI. Individuals over the age of 40 are excluded to provide a more homogeneous sample, to make this sample comparable to other research conducted at this institution and to decrease abnormalities in the outcome measures due to age-related changes.

You may qualify if:

• years old
• healthy
• can understand and respond to verbal directions while in an MRI

You may not qualify if:

• blind
• undergone treatment for brain tumor, stroke, intracranial hemorrhage
• diabetes or any other form of peripheral neuropathy
• require a pacemaker, insulin pump or other electronic equipment
• taking beta blocking medications, systemic steroid medications or other medications likely to affect autonomic or central nervous system function

Sponsors & Collaborators

• Wake Forest University: lead

Study Sites (1)

Center for Biomolecular Imaging and Center for Integrative Medicine, Wake Forest University

Winston-Salem, North Carolina, 27157, United States

Location

Study Officials

• Kathi Kemper, MD, MPH

  Wake Forest University Health Sciences

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 8, 2011
• First Posted: September 12, 2011
• Study Start: August 1, 2011
• Primary Completion: December 1, 2011
• Study Completion: December 1, 2011
• Last Updated: August 10, 2017

Record last verified: 2017-08

Locations

US (1)