NCT01430624

Brief Summary

The purpose of this study is to evaluate whether a brief intervention in video format, that includes education about reactions to assault and modeling of adaptive coping strategies, designed to reduce post assault drug use or abuse and PTSD and shown to recent victims of sexual assault at the time of receipt of post assault medical care is associated with better post-assault outcomes as compared to a comparable length video that includes pleasant imagery and relaxation instruction or standard care.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
245

participants targeted

Target at P75+ for phase_1

Timeline
Completed

Started May 2009

Longer than P75 for phase_1

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2009

Completed
2.4 years until next milestone

First Submitted

Initial submission to the registry

September 6, 2011

Completed
2 days until next milestone

First Posted

Study publicly available on registry

September 8, 2011

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2013

Completed
2.4 years until next milestone

Results Posted

Study results publicly available

April 13, 2016

Completed
Last Updated

April 13, 2016

Status Verified

April 1, 2015

Enrollment Period

4.6 years

First QC Date

September 6, 2011

Results QC Date

November 2, 2015

Last Update Submit

March 14, 2016

Conditions

Keywords

RapeSecondary preventionIntervention

Outcome Measures

Primary Outcomes (5)

  • Drug Abuse Screening Test (DAST-10)

    total possible scores range from 0 - 10 with higher scores indicating poor functioning, post assault at 6 months

    6 months

  • Alcohol Use Disorders Identification Test (AUDIT)

    Total scores range from 0 - 40 with higher scores indicating greater problem severity, post assault at 6 months

    6 months

  • Cigarettes (Estimated Number)

    quantity in 14 days prior to 6 week, 3 month and 6 month follow-up

    14 days preceding 6 week, 3 month and 6 month follow-up

  • Amount of Alcohol Use

    estimated number of drinks during the 14 days prior to each follow-up assessment

    14 days prior to 6 week, 3 month, 6 month follow-up

  • Marijuana Use Frequency

    Number of days of use within the 14 days prior to follow-up assessment

    14 days prior to 6 week, 3 month, 6 month follow-up

Secondary Outcomes (3)

  • Any Other Illicit Drug Use

    14 days prior to 6 week, 3 month, 6 month follow-up

  • Non-medical Use of Prescription Drugs Frequency

    14 days prior to 6 week, 3 month, 6 month follow-up

  • PTSD Symptom Scale Self-Report (PSS-SR)

    2 weeks prior to 6 week, 3 month, 6 month followup

Study Arms (3)

PPRS video

EXPERIMENTAL

Prevention of post sexual assault stress

Behavioral: PPRS

PIRI video

ACTIVE COMPARATOR

Pleasant imagery and relaxation instruction

Behavioral: PIRI

Standard care

NO INTERVENTION

Treatment as usual

Interventions

PPRSBEHAVIORAL

Video including information psychoeducation and modeling of adaptive behavioral coping strategies for use post-assault. Shown at time of post assault medical exam.

PPRS video
PIRIBEHAVIORAL

Video containing pleasant imagery and relaxation instruction information. Shown at time of post assault medical exam.

PIRI video

Eligibility Criteria

Age15 Years - 90 Years
Sexfemale
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Seeking medical care after recent sexual assault

You may not qualify if:

  • Active psychosis Active suicidality Cognitive impairment Non-English speaking Severe injury

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Hennepin County Medical Center

Minneapolis, Minnesota, 55404, United States

Location

North Memorial Medical Center

Minneapolis, Minnesota, 55422, United States

Location

Related Publications (4)

  • O'Doherty L, Whelan M, Carter GJ, Brown K, Tarzia L, Hegarty K, Feder G, Brown SJ. Psychosocial interventions for survivors of rape and sexual assault experienced during adulthood. Cochrane Database Syst Rev. 2023 Oct 5;10(10):CD013456. doi: 10.1002/14651858.CD013456.pub2.

  • Walsh K, Gilmore AK, Jaffe AE, Frazier P, Ledray L, Acierno R, Ruggiero KJ, Kilpatrick DG, Resnick HS. A preliminary examination of sexual and physical victimization 6 months after recent rape. Arch Womens Ment Health. 2023 Aug;26(4):495-501. doi: 10.1007/s00737-023-01335-y. Epub 2023 Jun 8.

  • Walsh K, Gilmore AK, Schumacher JA, Coffey SF, Frazier PA, Ledray L, Acierno R, Ruggiero KJ, Kilpatrick DG, Resnick HS. Post-sexual assault cigarette smoking: Findings from a randomized clinical trial of a video-based intervention. Addict Behav. 2020 Jan;100:106121. doi: 10.1016/j.addbeh.2019.106121. Epub 2019 Sep 5.

  • Gilmore AK, Walsh K, Frazier P, Ledray L, Acierno R, Ruggiero KJ, Kilpatrick DG, Resnick HS. Prescription Opioid Misuse After a Recent Sexual Assault: A Randomized Clinical Trial of a Video Intervention. Am J Addict. 2019 Sep;28(5):376-381. doi: 10.1111/ajad.12922. Epub 2019 Jun 26.

MeSH Terms

Conditions

Substance-Related DisordersStress Disorders, Post-Traumatic

Condition Hierarchy (Ancestors)

Chemically-Induced DisordersMental DisordersStress Disorders, TraumaticTrauma and Stressor Related Disorders

Results Point of Contact

Title
Heidi Resnick, Ph.D.
Organization
Medical University of South Carolina

Study Officials

  • Heidi Resnick, Ph.D.

    Medical University of South Carolina

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 6, 2011

First Posted

September 8, 2011

Study Start

May 1, 2009

Primary Completion

December 1, 2013

Study Completion

December 1, 2013

Last Updated

April 13, 2016

Results First Posted

April 13, 2016

Record last verified: 2015-04

Locations