NCT01429636

Brief Summary

The purpose of this study is to demonstrate better efficacy and effectiveness of modified applied relaxation technique over its original version for treating menopausal symptoms.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at below P25 for phase_3

Timeline
Completed

Started Aug 2011

Shorter than P25 for phase_3

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2011

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

September 1, 2011

Completed
6 days until next milestone

First Posted

Study publicly available on registry

September 7, 2011

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2011

Completed
Last Updated

December 30, 2011

Status Verified

December 1, 2011

Enrollment Period

4 months

First QC Date

September 1, 2011

Last Update Submit

December 28, 2011

Conditions

Keywords

perimenopausepostmenopausevasomotor symptomsrelaxation

Outcome Measures

Primary Outcomes (1)

  • Changes in global scores of Menopausal Rating Scale (MRS).

    MRS measure after intervention at 1, 2 and 3 months for follow-up.

    12 weeks

Secondary Outcomes (3)

  • Change in the frequency and severity of hot flushes.

    12 weeks

  • Change in the frequency and severity of night sweats.

    12 weeks

  • Change in the frequency and severity of sleep disturbances.

    12 weeks

Study Arms (2)

Applied Relaxation (AR)

EXPERIMENTAL
Behavioral: Applied Relaxation (AR)

Modified Relaxation (MR)

EXPERIMENTAL
Behavioral: Modified Relaxation (MR)

Interventions

The MR technique is modified from the AR technique that will require participants to attend only 1 session, lasting 60 minutes. After the training session, participants will be given a hand-out on MR. They will continue to practice MR at home once a day for 15-20 minutes during their leisure times, at least 5 days a week for the whole 12 weeks of the follow-up period.

Also known as: Behavioral relaxation
Modified Relaxation (MR)

Participants will receive 12 sessions AR training. After that they will asked to practice at home once a day for 15-20 minutes during their leisure times, at least 5 days a week for the whole 12 weeks of the follow-up period.

Also known as: Behavioral Applied Relaxation
Applied Relaxation (AR)

Eligibility Criteria

Age45 Years - 65 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Perimenopausal women and postmenopausal women with either surgical or spontaneous menopause.
  • Women who have at least 5 points of MRS score.

You may not qualify if:

  • Women who are taking any hormone therapy for any reason in the past three months prior to entering the trails.
  • Women with uncontrolled hypertension (\>95mmHg diastolic pressure) or daily use of sedatives, tranquilizer or antidepressant medication.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Mahassarakham Hospital

Maha Sarakham, Northeast, 44000, Thailand

Location

Related Links

MeSH Terms

Conditions

Hot FlashesParasomnias

Condition Hierarchy (Ancestors)

Signs and SymptomsPathological Conditions, Signs and SymptomsSleep Wake DisordersNervous System DiseasesMental Disorders

Study Officials

  • Suprawita - Saensak, PhDcandidate

    PhD in Clinical Epidemiology Program, Faculty of Medicine, Chiang Mai University (Thailand)

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Phase 3 Study of Applied Relaxation (AR) Technique versus Its Modified Version for Treating Menopausal Symptoms.

Study Record Dates

First Submitted

September 1, 2011

First Posted

September 7, 2011

Study Start

August 1, 2011

Primary Completion

December 1, 2011

Study Completion

December 1, 2011

Last Updated

December 30, 2011

Record last verified: 2011-12

Locations