Effects of an Innovative Balance Training Programme in Enhancing Postural Control and Reducing Falls in Patients With Parkinson's Disease
1 other identifier
interventional
52
1 country
1
Brief Summary
Falling is a complex and most disabling feature for patients with Parkinson's disease (PD). Previous studies suggested that falls in patients with PD are related to postural instability characterized by deficits in anticipatory postural adjustment (APA) for postural orientation in walking and standing and inadequate postural response to perturbation. The present study developed an innovative balance treatment with focus of anticipatory and compensatory postural control and examined its effects on enhancing balance and gait performance and decreasing fall rate in people with PD.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Mar 2009
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 1, 2009
CompletedFirst Submitted
Initial submission to the registry
August 30, 2011
CompletedFirst Posted
Study publicly available on registry
September 1, 2011
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2012
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2012
CompletedSeptember 1, 2011
August 1, 2011
3 years
August 30, 2011
August 30, 2011
Conditions
Keywords
Outcome Measures
Primary Outcomes (6)
reaction time of limits of stability test
One year
one-leg-stance time
one year
pull test
it reflects the ability of compensatory postural control in patients with Parkinson's disease
one year
fall rate
previous one year before baseline assessment, each following one month for 3-month of training and 12-month of follow-up
movement velocity of limit of stability test
one year
end point excursion of limits of stability test
One year
Secondary Outcomes (4)
Unified Parkinson's Disease rating scale- motor examination subscale
one year
Gait velocity
one year
Stride length
One year
Cadence
One year
Study Arms (2)
anticipatory and compensatory postural control training
EXPERIMENTALSubjects in the experimental group were trained the speed and amplitude of anticipatory postural adjustment during fall-prone activities and postural response to perturbation during walking. Training was provided with preparatory cues, computerized machines and treadmill.
strength-focused training
ACTIVE COMPARATORSubjects in control group were provided with strength training of leg muscles using machines and during functional activities.
Interventions
Subjects in the experimental group were trained the speed and amplitude of anticipatory postural adjustment during fall-prone activities and postural response to perturbation during walking. Training was provided with preparatory cues, computerized machines and treadmill.
Subjects in control group were provided with strength training of leg muscles using machines and during functional activities.
Eligibility Criteria
You may qualify if:
- diagnosed as parkinson's disease
- years old or above
- stable on anti-parkinsonian medications for at least 6 weeks prior to entry into the study, which will remain unchanged for the duration of the study
- able to walk a 10 meter distance at least 3 times with or without walking aids independently
- at stage 2 or 3 of the Hoehn and Yahr staging
- able to provide informed consent
You may not qualify if:
- neurological conditions other than PD
- uncompensated cardiovascular disease
- less than 23 score on the Mini-Mental State examination,
- History of fracture or recent musculoskeletal disorders in back or lower limbs which would interfere with the balance during exercise and daily activities
- visual disturbance or vestibular dysfunction limiting locomotion or balance
- participation in other balance-related training program more than one time per week
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
the Hong Kong Polytechnic University
Hong Kong, Hong Kong, China
Related Publications (2)
Ernst M, Folkerts AK, Gollan R, Lieker E, Caro-Valenzuela J, Adams A, Cryns N, Monsef I, Dresen A, Roheger M, Eggers C, Skoetz N, Kalbe E. Physical exercise for people with Parkinson's disease: a systematic review and network meta-analysis. Cochrane Database Syst Rev. 2024 Apr 8;4(4):CD013856. doi: 10.1002/14651858.CD013856.pub3.
PMID: 38588457DERIVEDErnst M, Folkerts AK, Gollan R, Lieker E, Caro-Valenzuela J, Adams A, Cryns N, Monsef I, Dresen A, Roheger M, Eggers C, Skoetz N, Kalbe E. Physical exercise for people with Parkinson's disease: a systematic review and network meta-analysis. Cochrane Database Syst Rev. 2023 Jan 5;1(1):CD013856. doi: 10.1002/14651858.CD013856.pub2.
PMID: 36602886DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Xia SHEN, PHD candidate
Department of Rehabilitation Sciences, The Hong Kong Polytechnic University
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor
Study Record Dates
First Submitted
August 30, 2011
First Posted
September 1, 2011
Study Start
March 1, 2009
Primary Completion
March 1, 2012
Study Completion
June 1, 2012
Last Updated
September 1, 2011
Record last verified: 2011-08