NCT01411254

Brief Summary

This study will evaluate the efficacy and safety of Betamethasone Microsphere (DE-102) for diabetic macular edema.

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 4, 2011

Completed
4 days until next milestone

First Posted

Study publicly available on registry

August 8, 2011

Completed
Last Updated

July 21, 2014

Status Verified

July 1, 2014

First QC Date

August 4, 2011

Last Update Submit

July 17, 2014

Conditions

Keywords

DME

Outcome Measures

Primary Outcomes (1)

  • Best Corrected Visual Acuity(BCVA)

    Change from baseline of Best Corrected Visual Acuity(BCVA) in ETDRS letter score

Secondary Outcomes (1)

  • retinal thickness

Study Arms (3)

1

EXPERIMENTAL
Drug: Betamethasone Microsphere (DE-102) Low Dose

2

EXPERIMENTAL
Drug: Betamethasone Microsphere (DE-102) High Dose

3

SHAM COMPARATOR
Drug: Sham

Interventions

Eligibility Criteria

Age20 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Provided signed, written informed consent
  • years of age or older with diabetic macular edema

You may not qualify if:

  • Active proliferative diabetic retinopathies (PDR) in the study eye
  • Uncontrolled diabetes mellitus and hypertension
  • Known steroid-responder

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Santen study sites

Osaka, Osaka, Japan

Location

MeSH Terms

Interventions

salicylhydroxamic acid

Study Design

Study Type
interventional
Phase
phase 2
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

August 4, 2011

First Posted

August 8, 2011

Last Updated

July 21, 2014

Record last verified: 2014-07

Locations