NCT01407445

Brief Summary

Objective: To study the effects of Tribulus terrestris on sexuality in postmenopausal women.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for phase_4

Timeline
Completed

Started Jan 2009

Typical duration for phase_4

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2009

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2011

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

August 1, 2011

Completed
1 day until next milestone

First Posted

Study publicly available on registry

August 2, 2011

Completed
Last Updated

November 10, 2015

Status Verified

November 1, 2015

Enrollment Period

2.3 years

First QC Date

August 1, 2011

Last Update Submit

November 9, 2015

Conditions

Keywords

MenopauseSexual dysfunctionTribulusSexualityPhytotherapeutic Drugs

Outcome Measures

Primary Outcomes (1)

  • Sexual function in post-menopausal women

    Based the questionnaires Golombok-Rust Inventory of Sexual Satisfaction (GRISS) and Sexual Quotient - female version (SQF).

    90 days

Secondary Outcomes (1)

  • Female Intervention Efficacy Index (FIEI)

    3 months

Study Arms (2)

Placebo

PLACEBO COMPARATOR

1 tablet of placebo/ oral/ 3 times a day for three months

Drug: Placebo

Tribulus terrestris

ACTIVE COMPARATOR

1 tablet of 250mg/ oral/ 3 times a day for three months

Drug: Tribulus terrestris

Interventions

1 tablet/ oral/ 3 times a day for 90 days

Also known as: lot 168159
Placebo

1 tablet of 250mg/ oral/ 3 times a day for 90 days

Also known as: lot 168059
Tribulus terrestris

Eligibility Criteria

Age40 Years - 70 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Women past menopause, with full autonomy, at least one year of amenorrhea and FSH\> 30 mIU / mL.
  • Sexually active
  • Partner is stable and without sexual difficulties
  • Carrier sexual abuse (desire, arousal, orgasm and dyspareunia)

You may not qualify if:

  • Women on hormone therapy within the preceding 12 months
  • Women without sexual activity
  • With diabetes mellitus
  • Patients with cognitive impairment
  • Patients with hormone-dependent tumor
  • History of psychiatric illness
  • Patients with liver disease
  • Patients with kidney disease
  • Users of drugs with proven to decrease sexual desire
  • Cardivascular disease, renal disease.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Santa Casa of Sao Paulo Medical School

São Paulo, São Paulo, Brazil

Location

MeSH Terms

Conditions

Sexual Dysfunction, PhysiologicalSexuality

Interventions

Tribulus extract

Condition Hierarchy (Ancestors)

Genital DiseasesUrogenital DiseasesSexual BehaviorBehavior

Study Officials

  • Sonia lima, PhD

    Faculdade de Ciências Médicas da Santa Casa de São Paulo

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Study of the Effects of Tribulus Terrestris on Sexuality in Postmenopausal Women

Study Record Dates

First Submitted

August 1, 2011

First Posted

August 2, 2011

Study Start

January 1, 2009

Primary Completion

May 1, 2011

Study Completion

May 1, 2011

Last Updated

November 10, 2015

Record last verified: 2015-11

Locations