Computer-Based Training in Cognitive Behavior Therapy (CBT4CBT)

NCT01406899 | Completed Phase 1 DMC

• 1 other identifier: JC0008
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

In this behavioral trial 80 substance abusing individuals will be randomly assigned to either treatment as usual in the substance abuse clinic of the Newington, CT VA hospital OR treatment as usual plus 8 hours of access to the 'CBT for CBT' computer program over a period of 8 weeks. Primary outcomes will be retention in treatment and reduction in substance use (percent days abstinent, confirmed by urine toxicology screens). The patients' ability to demonstrate coping skills through a computerized role-play evaluation will be a secondary outcome. A six-month follow-up will assess durability and/or delayed emergence of effects.

Conditions

Substance-Related Disorders

Outcome Measures

Primary Outcomes (1)

• Reduction in substance use

  percent days abstinent, confirmed by urine toxicology screens

  8 weeks

Secondary Outcomes (1)

• Retention in treatment

  6 months

Study Arms (2)

Treatment as Usual

NO INTERVENTION

Standard treatment as usual (TAU) in the VA Connecticut Healthcare System substance abuse clinic consisting of individual and group therapy sessions and regular urine monitoring.

Computer-based treatment

EXPERIMENTAL

Standard treatment as usual (TAU) plus coping skills computer program. In addition to the individual and group therapy sessions (TAU), individuals will work with a computerized program that teaches skills for stopping substance use and increasing coping skills twice weekly for 8 weeks.

Behavioral: Computer Based Treatment

Interventions

Computer Based Treatment BEHAVIORAL

Standard treatment as usual (TAU) plus coping skills computer program. In addition to the individual and group therapy sessions (TAU), individuals will work with a computerized program that teaches skills for stopping substance use and increasing coping skills twice weekly for 8 weeks.

Also known as: Cognitive Behavioral Therapy

Computer-based treatment

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• years and older
• Recent (within 3 months) substance use
• meet current DSM-IV (Diagnostic and Statistical Manual-IV) criteria for substance use disorder
• fluent in English or at least a 6th grade reading level
• can commit to at least 8 weeks of treatment and willing to be randomized to treatment

You may not qualify if:

• Unstable housing situation
• Likelihood of going to prison during the intervention portion of study
• Recent opiate or benzodiazepine prescription

Sponsors & Collaborators

• VA Connecticut Healthcare System: lead

Study Sites (1)

Connecticut VA Healthcare System

Newington, Connecticut, 06111, United States

Location

Related Publications (1)

• Lichenstein SD, Kohler R, Ye F, Potenza MN, Kiluk B, Yip SW. Distinct neural networks predict cocaine versus cannabis treatment outcomes. Mol Psychiatry. 2023 Aug;28(8):3365-3372. doi: 10.1038/s41380-023-02120-0. Epub 2023 Jun 12.

  PMID: 37308679 DERIVED

MeSH Terms

Conditions

Substance-Related Disorders

Interventions

Cognitive Behavioral Therapy

Condition Hierarchy (Ancestors)

Chemically-Induced Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Behavior Therapy; Psychotherapy; Behavioral Disciplines and Activities

Study Officials

• Kathleen Carroll, Ph.D.

  Yale University

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: phase 1
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: FED
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 27, 2011
• First Posted: August 1, 2011
• Study Start: January 1, 2010
• Primary Completion: May 1, 2013
• Study Completion: December 1, 2013
• Last Updated: December 23, 2014

Record last verified: 2012-03

Locations

US (1)