NCT01403493

Brief Summary

In this randomized controlled study in patients with irritable bowel syndrome (IBS), the investigators plan to compare the effects of a multidisciplinary structured patient group education with a compressed nurse based structured patient group education. The effects of the interventions on gastrointestinal (GI) and psychological symptom severity, knowledge and quality of life will be assessed with validated questionnaires at baseline and 3, 6 and 12 months after the intervention.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Aug 2007

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2007

Completed
3.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2011

Completed
24 days until next milestone

First Submitted

Initial submission to the registry

July 25, 2011

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 27, 2011

Completed
Last Updated

August 11, 2011

Status Verified

July 1, 2011

Enrollment Period

3.9 years

First QC Date

July 25, 2011

Last Update Submit

August 9, 2011

Conditions

Keywords

Irritable bowel syndromePatient education

Outcome Measures

Primary Outcomes (1)

  • Effect on GI symptoms as measured by IBS-SSS and satisfactory relief of IBS symptoms

    Change from Baseline in GI Symptom severity and satisfactory relief of IBS symptoms at 3, 6 and 12 months.

Secondary Outcomes (1)

  • Effects on Quality of life (IBSQOL), Psychological symptoms (HAD), GI specific anxiety (VSI) and knowledge about IBS

    Change from Baseline in quality of life, psychological symptoms and knowledge at 3, 6 and 12 months.

Study Arms (2)

Multidisciplinary patient education

ACTIVE COMPARATOR

A multidisciplinary (nurse, gastroenterologist, dietician, physiotherapist, psychologist) group education with six sessions for patients with IBS.

Behavioral: Patient education

Nurse based patient education

ACTIVE COMPARATOR

A nurse based patient education with three sessions for patients with IBS.

Behavioral: Patient education

Interventions

Multidisciplinary patient educationNurse based patient education

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Men and women 18 to 70 years old, with IBS according to the Rome II criteria.
  • Written informed consent

You may not qualify if:

  • An organic GI disease and/or with another disease potentially affecting the GI symptoms.
  • Severe psychiatric disease.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Dept of Internal Medicine, Sahlgrenska University Hospital

Gothenburg, S413-45, Sweden

Location

MeSH Terms

Conditions

Irritable Bowel Syndrome

Interventions

Patient Education as Topic

Condition Hierarchy (Ancestors)

Colonic Diseases, FunctionalColonic DiseasesIntestinal DiseasesGastrointestinal DiseasesDigestive System Diseases

Intervention Hierarchy (Ancestors)

Health EducationPreventive Health ServicesHealth ServicesHealth Care Facilities Workforce and Services

Study Officials

  • Magnus Simren, MD, PhD

    Sahlgrenska University Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

July 25, 2011

First Posted

July 27, 2011

Study Start

August 1, 2007

Primary Completion

July 1, 2011

Study Completion

July 1, 2011

Last Updated

August 11, 2011

Record last verified: 2011-07

Locations