International Multicenter Registry for Mechanical Recanalization Procedures in Acute Stroke
ENDOSTROKE
1 other identifier
observational
500
2 countries
13
Brief Summary
The purpose of the Endostroke Registry is to gather information on predictors of good or poor clinical outcome following mechanical recanalization therapies for acute ischemic stroke.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
13 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2011
CompletedFirst Submitted
Initial submission to the registry
July 18, 2011
CompletedFirst Posted
Study publicly available on registry
July 22, 2011
CompletedJuly 22, 2011
July 1, 2011
July 18, 2011
July 21, 2011
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Clinical outcome
Proportion of patients with favourable clinical outcome defined as a Modified Rankin Score (MRS) of 0,1, or 2 three months after the intervention.
approx. 90 days after stroke onset
Secondary Outcomes (2)
Angiographic outcome
Day of intervention
Complication rate
within 36 h after endovascular procedure
Study Arms (1)
mechanical recanalization
Patients with acute stroke being treated with endovascular devices for mechanical recanalization (no restriction to specific endovascular devices)
Interventions
Endovascular thrombus extraction by mechanical recanalization devices
Eligibility Criteria
Patients with acute ischemic stroke being treated with mechanical recanalization devices for proximal vessel occlusion of brain supplying arteries (i.e. MCA main stem occlusion, basilar artery occlusion, distal ICA occlusion)
You may qualify if:
- Patients being treated with mechanical recanalization devices due to an acute proximal arterial vessel occlusion of brain supplying arteries
You may not qualify if:
- Patients being treated with mechanical recanalization devices for venous vessel occlusion.
- Patients being treated with mechanical recanalization devices due to an acute vessel occlusion which occured as a complication of an angiographic procedure scheduled for other reasons (i.e. as a complication of a diagnostic angiography or coiling procedure for cerebral aneurysms)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (13)
Departments of Neurology and Neuroradiology, University Hospital
Graz, 8036, Austria
Departments of Neurology and Neuroradiology, Landes-Nervenklinik Wagner-Jauregg
Linz, 4020, Austria
Departments of Neurology and Neuroradiology, University Hospital
Aachen, 52074, Germany
Departments of Neurology and Radiology, Klinikum Altenburger Land
Altenburg, 04600, Germany
Departments of Neurology and Neuroradiology, Charite University Hospital
Berlin, 10117, Germany
Departments of Neurology and Neuroradiology, University Hospital
Düsseldorf, 40255, Germany
Departments of Neurology and Neuroradiology, University Hospital
Essen, 45122, Germany
Hirngefaesszentrum Goethe University
Frankfurt, 60528, Germany
Departments of Neurology and Neuroradiology, Klinikum Fulda
Fulda, 36043, Germany
Departments of Neurology and Neuroradiology, University Hospital
Giessen, 35385, Germany
Departments of Neurology and Neuroradiology, University Hospital
Kiel, 24105, Germany
Departments of Neurology and Neuroradiology, University Hospital
Mainz, 55131, Germany
Departments of Neurology and Neuroradiology, Knappschaftskrankenhaus
Recklinghausen, 45657, Germany
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Oliver C. Singer, MD
Hirngefaesszentrum Goethe University Frankfurt Germany
- PRINCIPAL INVESTIGATOR
Joachim Berkefeld, MD
Hirngefaesszentrum Goethe University Frankfurt Germany