NCT01399502

Brief Summary

The purpose of this study is to investigate the effectiveness of health promotion emails for depression. It is hypothesised that emails containing self-help advice will improve depression symptoms more than emails containing information about depression.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,736

participants targeted

Target at P75+ for phase_1

Timeline
Completed

Started Nov 2011

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 19, 2011

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 21, 2011

Completed
3 months until next milestone

Study Start

First participant enrolled

November 1, 2011

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2012

Completed
Last Updated

December 11, 2013

Status Verified

December 1, 2013

Enrollment Period

1.1 years

First QC Date

July 19, 2011

Last Update Submit

December 9, 2013

Conditions

Keywords

DepressionSelf Care

Outcome Measures

Primary Outcomes (2)

  • Depression symptom score on PHQ-9 at post-intervention

    6-weeks post baseline

  • Depression symptom score on PHQ-9 at 6-month follow-up

    6-months post end-of-intervention

Secondary Outcomes (4)

  • Psychological distress on K10 at post-intervention

    6-weeks post baseline

  • Psychological functioning on Work and Social Adjustment Scale at post-intervention

    6-weeks post baseline

  • Psychological functioning on Work and Social Adjustment Scale at 6-month follow-up

    6-months post end-of-intervention

  • Psychological distress on K10 at 6-month follow-up

    6-months post end-of-intervention

Study Arms (2)

Self-help advice

ACTIVE COMPARATOR

Each email will contain a self-help strategy for coping with depressive symptoms. The email will contain information about why the strategy will be effective, tips for implementing the strategy and overcoming barriers, and how to set a goal to implement the strategy. Strategies are based on previous research published by the trial co-ordinators.

Behavioral: Mood Memo emails

Depression information

PLACEBO COMPARATOR

Each email will contain different information about depression, such as symptoms, risk factors, prevalence.

Behavioral: Mood Memo emails

Interventions

Participants will receive 12 emails over 6 weeks.

Depression informationSelf-help advice

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Access to the internet at least once per week
  • Resident of Australia, New Zealand, Canada, Ireland, United Kingdom, USA

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Orygen Youth Health Research Centre

Parkville, Victoria, 3052, Australia

Location

Related Publications (1)

  • Morgan AJ, Jorm AF, Mackinnon AJ. Self-Help for Depression via E-mail: A Randomised Controlled Trial of Effects on Depression and Self-Help Behaviour. PLoS One. 2013 Jun 21;8(6):e66537. doi: 10.1371/journal.pone.0066537. Print 2013.

MeSH Terms

Conditions

Depressive DisorderDepression

Condition Hierarchy (Ancestors)

Mood DisordersMental DisordersBehavioral SymptomsBehavior

Study Officials

  • Anthony F Jorm, PhD, DSc

    Orygen Youth Health Research Centre, The University of Melbourne

    PRINCIPAL INVESTIGATOR
  • Andrew J Mackinnon, PhD

    Orygen Youth Health Research Centre, The University of Melbourne

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PhD candidate

Study Record Dates

First Submitted

July 19, 2011

First Posted

July 21, 2011

Study Start

November 1, 2011

Primary Completion

December 1, 2012

Study Completion

December 1, 2012

Last Updated

December 11, 2013

Record last verified: 2013-12

Locations