Attentional Bias in Body Dysmorphic Disorder

NCT01398904 | Completed

• 1 other identifier: 2010P002912
• Study Type: observational
• Target: 51
• Locations: 1 country
• Sites: 1

Brief Summary

Body Dysmorphic Disorder (BDD) participants will demonstrate greater attentional biases as compared to healthy control (HC) participants. Greater attention bias will be associated with greater distress. Greater attention bias will be associated with greater symptom severity.

Conditions

Body Dysmorphic Disorders

Keywords

BDD

Outcome Measures

Primary Outcomes (1)

• Attention Pattern

  Gaze tracking via an Eyelink II eye tracker will determine perception of visual information.

  Day 2

Secondary Outcomes (2)

• Subjective Units of Distress Scale (SUDS)

  Day 2

• Facial Attractiveness

  Day 2

Study Arms (2)

Body dysmorphic disorder (BDD) Participants

Participants must be 18 years or older with a primary diagnosis of body dysmorphic disorder (BDD), a BDD Yale-Brown Obsessive Compulsive Scale (BDDY-BOCS) score of \>20, and a primary facial/head concern. Participants must have the ability to provide informed consent and understand study staff.

Healthy Controls

Males and females 18 years of age or older with ability to provide informed consent and understand study staff.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The study will include 40 participants, consisting of 20 BDD participants and 20 matched healthy controls.

You may qualify if:

• males and females 18 years of age or older
• sufficient fluency of English to understand study staff, procedures, and questionnaires
• ability to provide informed consent
• primary diagnosis of Diagnostic and Statistical Manual 4th Edition (DSM-IV-TR) BDD
• BDD Yale-Brown Obsessive Compulsive Disorder score (Y-BOCS) of \> 20
• primary facial/head concern

You may not qualify if:

• Major medical or neurological conditions
• schizophrenia, schizoaffective disorder, or any other current lifetime DSM-IV psychotic disorder that is not attributable to delusional BDD
• current suicidality
• current homicidality
• Any current Axis I psychiatric illness
• history of BDD

Sponsors & Collaborators

• Massachusetts General Hospital: lead

Study Sites (1)

Massachusetts General Hospital

Boston, Massachusetts, 02114, United States

Location

Related Publications (10)

• Deckersbach T, Savage CR, Phillips KA, Wilhelm S, Buhlmann U, Rauch SL, Baer L, Jenike MA. Characteristics of memory dysfunction in body dysmorphic disorder. J Int Neuropsychol Soc. 2000 Sep;6(6):673-81. doi: 10.1017/s1355617700666055.

  PMID: 11011514 BACKGROUND

• Phillips KA. Quality of life for patients with body dysmorphic disorder. J Nerv Ment Dis. 2000 Mar;188(3):170-5. doi: 10.1097/00005053-200003000-00007.

  PMID: 10749282 BACKGROUND

• Phillips KA, Coles ME, Menard W, Yen S, Fay C, Weisberg RB. Suicidal ideation and suicide attempts in body dysmorphic disorder. J Clin Psychiatry. 2005 Jun;66(6):717-25. doi: 10.4088/jcp.v66n0607.

  PMID: 15960564 BACKGROUND

• Phillips KA, Menard W, Fay C, Pagano ME. Psychosocial functioning and quality of life in body dysmorphic disorder. Compr Psychiatry. 2005 Jul-Aug;46(4):254-60. doi: 10.1016/j.comppsych.2004.10.004.

  PMID: 16175755 BACKGROUND

• Savage CR, Baer L, Keuthen NJ, Brown HD, Rauch SL, Jenike MA. Organizational strategies mediate nonverbal memory impairment in obsessive-compulsive disorder. Biol Psychiatry. 1999 Apr 1;45(7):905-16. doi: 10.1016/s0006-3223(98)00278-9.

  PMID: 10202579 BACKGROUND

• Kelly MM, Walters C, Phillips KA. Social anxiety and its relationship to functional impairment in body dysmorphic disorder. Behav Ther. 2010 Jun;41(2):143-53. doi: 10.1016/j.beth.2009.01.005. Epub 2009 Oct 7.

  PMID: 20412881 BACKGROUND

• Maner JK, Holm-Denoma JM, Van Orden KA, Gailliot MT, Gordon KH, Joiner TE Jr. Evidence for attentional bias in women exhibiting bulimotypic symptoms. Int J Eat Disord. 2006 Jan;39(1):55-61. doi: 10.1002/eat.20222.

  PMID: 16231350 BACKGROUND

• Roefs A, Jansen A, Moresi S, Willems P, van Grootel S, van der Borgh A. Looking good. BMI, attractiveness bias and visual attention. Appetite. 2008 Nov;51(3):552-5. doi: 10.1016/j.appet.2008.04.008. Epub 2008 Apr 15.

  PMID: 18495295 BACKGROUND

• Carey P, Seedat S, Warwick J, van Heerden B, Stein DJ. SPECT imaging of body dysmorphic disorder. J Neuropsychiatry Clin Neurosci. 2004 Summer;16(3):357-9. doi: 10.1176/jnp.16.3.357.

  PMID: 15377744 BACKGROUND

• Janelle CM, Hausenblas HA, Fallon EA, Gardner RE. A visual search examination of attentional biases among individuals with high and low drive for thinness. Eat Weight Disord. 2003 Jun;8(2):138-44. doi: 10.1007/BF03325003.

  PMID: 12880191 BACKGROUND

MeSH Terms

Conditions

Body Dysmorphic Disorders

Condition Hierarchy (Ancestors)

Somatoform Disorders; Mental Disorders

Study Officials

• Sabine Wilhelm, Ph. D.

  Massachusetts General Hospital

  PRINCIPAL INVESTIGATOR

• Jennifer Greenberg, Psy. D.

  Massachusetts General Hospital

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Director, OCD & Related Disorders Program

Study Record Dates

• First Submitted: July 15, 2011
• First Posted: July 21, 2011
• Study Start: March 1, 2011
• Primary Completion: July 1, 2012
• Study Completion: July 1, 2012
• Last Updated: December 3, 2014

Record last verified: 2014-12

Locations

US (1)