Respiratory Quotient in Post Roux-en-Y Gastric Bypass Patients

NCT01396460 | Completed

• 1 other identifier: NCT01231087
• Study Type: observational
• Target: 69
• Locations: 1 country
• Sites: 1

Brief Summary

Through the values of respiratory quotient (RQ) it is possible to estimate the utilization of energy substrates by the body, or if there is a higher or lower fat oxidation. Experimental and clinical studies have shown that after Roux-en-Y Gastric Bypass (RYGBP) there is a decrease in the values of RQ, which may be associated with increased lipid oxidation in the postoperative period. Diet Induced Thermogenesis (DIT) is an important part of Total Energy Expenditure. We would like to know how it functions among RYGBP patients. The purpose of this study is to evaluate the RQ and DIT of patients in the post operative phase and compare the result with a control group consisting of morbid obese population.

Conditions

Morbid Obesity

Keywords

respiratory quotient; fat oxidation; morbid obesity; bariatric; Bariatric Surgery

Outcome Measures

Primary Outcomes (1)

• Diet Induced Thermogenesis

  To examine the possible changes in the thermic effect of food, the patients received a standard meal. They then repeated the test 20 minutes after eating to obtain a reading of the metabolic rate by considering the DIT and RQ in the postprandial period. DIT was calculated as the difference between post prandial metabolic rate and RMR.

  20min after standard meal

Study Arms (2)

bariatric patients

Bariatric post operative patients were compared with morbid obese population

Other: breakfast (a chicken sandwich with juice)

control group

morbid obese population

Interventions

breakfast (a chicken sandwich with juice) OTHER

patients received a breakfast after de initial measurement

bariatric patients

Eligibility Criteria

• Age: 20 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Bariatric post operative population

You may qualify if:

• With more than 1 year after surgery
• Consent given to participate

You may not qualify if:

• Pregnant women
• Malnourished patients (anemia)
• Tiroid disorders without treatment

Sponsors & Collaborators

• Gastrocirurgia, Brazil: lead

Study Sites (1)

Gastrocirurgia de Brasilia

Brasília, Federal District, 70390108, Brazil

Location

MeSH Terms

Conditions

Obesity, Morbid

Interventions

Breakfast

Condition Hierarchy (Ancestors)

Obesity; Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Meals; Food; Diet, Food, and Nutrition; Physiological Phenomena; Food and Beverages

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Silvia Leite Faria , MSc, RD

Study Record Dates

• First Submitted: July 15, 2011
• First Posted: July 18, 2011
• Study Start: May 1, 2011
• Primary Completion: June 1, 2011
• Study Completion: July 1, 2011
• Last Updated: September 10, 2012

Record last verified: 2012-09

Locations

BR (1)