NCT01389336

Brief Summary

The aim of this study is to evaluate the effectiveness of an additive complex āyurvedic diagnosis and treatment compared to conventional standard care alone in stationary patients with Fibromyalgia Syndrome.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
31

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Jul 2011

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2011

Completed
5 days until next milestone

First Submitted

Initial submission to the registry

July 6, 2011

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 8, 2011

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2013

Completed
Last Updated

May 8, 2013

Status Verified

May 1, 2013

Enrollment Period

1.8 years

First QC Date

July 6, 2011

Last Update Submit

May 7, 2013

Conditions

Keywords

Fibromyalgia SyndromeFibromyalgiaAyurvedaTraditional Indian MedicineCAMPainChronic Widespread Pain

Outcome Measures

Primary Outcomes (1)

  • Fibromyalgia Impact Questionnaire (FIQ)

    Change in FIQ after completion of IPD-treatment

    max. 3 weeks

Secondary Outcomes (8)

  • Functional Hanover Questionnaire (FFBH)

    max. 3 weeks

  • State Trait Anxiety Inventory (STAI)

    max. 3 weeks

  • Profile of Mood States (POMS)

    max. 3 weeks

  • Short Form 36 Health Survey (SF-36)

    max. 3 weeks

  • VAS for pain

    max 3 weeks

  • +3 more secondary outcomes

Study Arms (2)

Add-on Ayurveda - Group

In the Āyurveda add-on-group 20 patients will receive individualized treatment according to the Āyurveda diagnosis which may include manual treatments, massages, dietary advice, specific consideration of selected food items, āyurvedic lifestyle \& yoga posture advice and daily self-applied massage on top of standard care.

Standard Care

20 Patients will receive the individually adjusted complex conventional standard care according to the current AWMF-guidelines including physiotherapy, occupational therapy, specific pain therapy and psychotherapy.

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Men and Women with Fibromyalgia-Syndrome between 18 und 70 years of age

You may qualify if:

  • informed consent
  • age between 18 and 70 years
  • FMS according to current guidelines

You may not qualify if:

  • pregnancy or breat feeding
  • acute psychiatric condition
  • severe acute somatic disease
  • severechronic comorbidity
  • obesity WHO \>= II degree
  • bloodcoagulation-disease
  • intake of opiods
  • current treatment with hyperthermia
  • simultaneous participant in other trial

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Immanuel Hospital Berlin

Berlin, State of Berlin, 14109, Germany

Location

Related Publications (1)

  • Kessler CS, Ostermann T, Meier L, Stapelfeldt E, Schutte S, Duda J, Michalsen A. Additive Complex Ayurvedic Treatment in Patients with Fibromyalgia Syndrome Compared to Conventional Standard Care Alone: A Nonrandomized Controlled Clinical Pilot Study (KAFA Trial). Evid Based Complement Alternat Med. 2013;2013:751403. doi: 10.1155/2013/751403. Epub 2013 Sep 1.

Related Links

MeSH Terms

Conditions

FibromyalgiaPainChronic Pain

Condition Hierarchy (Ancestors)

Muscular DiseasesMusculoskeletal DiseasesRheumatic DiseasesNeuromuscular DiseasesNervous System DiseasesNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Andreas Michalsen, Prof. Dr.

    Charité Medical University Berlin Germany

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Prof. Dr. Andreas Michalsen

Study Record Dates

First Submitted

July 6, 2011

First Posted

July 8, 2011

Study Start

July 1, 2011

Primary Completion

May 1, 2013

Study Completion

May 1, 2013

Last Updated

May 8, 2013

Record last verified: 2013-05

Locations