Pulmonary Arterial Hypertension Quality Enhancement Research Initiative Extension Program
PAH QuERI Ext
1 other identifier
observational
797
2 countries
76
Brief Summary
Knowledge Translation Program for the guidelines and evidence-based management of PAH patients
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jun 2011
Longer than P75 for all trials
76 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 1, 2011
CompletedFirst Submitted
Initial submission to the registry
July 6, 2011
CompletedFirst Posted
Study publicly available on registry
July 8, 2011
CompletedPrimary Completion
Last participant's last visit for primary outcome
April 10, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
April 10, 2018
CompletedAugust 15, 2018
August 1, 2018
6.9 years
July 6, 2011
August 14, 2018
Conditions
Outcome Measures
Primary Outcomes (1)
Patients achieving guideline-recommended treatment
Proportion of patients achieving guideline-recommended treatment
3 years
Secondary Outcomes (1)
Patients achieving optimal functional class
3 years
Study Arms (1)
Standard of care
Observational study to improve the management of PAH patients through an evidence-based approach aimed at achieving optimal WHO functional class (FC) treated with Tracleer, Ventavis, Veletri, Opsumit and/or Uptravi.
Interventions
observational study with patients treated with Tracleer, Ventavis, Veletri, Opsumit and/or Uptravi
Eligibility Criteria
Approximately 800 PAH patients from approximately 80 physician practices will be included in the program.
You may qualify if:
- Male and female adults (≥ 18 years of age)
- Documented diagnosis of PAH (all of the following): i. RHC demonstrating mPAP \> 25 mm Hg and PCWP
- ≤ 15 and PVR \> 3 ii. FEV 1 \> 50% predicted normal iii. V/Q and/or CT scan excluding the thromboembolic etiology
- Diagnosis of PAH \< 3 years
- Need for PAH specific treatment
- Desire to participate and signs an informed consent
You may not qualify if:
- Any of the criteria below:
- Poor mental function, drug or substance (e.g.,alcohol) abuse, or unstable psychiatric illness, which, in the opinion of the investigator, may interfere with optimal participation in the study
- Prior participation in this program
- Patients with pulmonary hypertension classified as group 2 - 5 Updated Clinical Classification of Pulmonary Hypertension (5th World Symposium on PH Modified Classification of PH)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Actelionlead
- Canadian Heart Research Centrecollaborator
Study Sites (76)
Cardiovascular Associates, PC
Birmingham, Alabama, 35216, United States
University of South Alabama Medical Center
Mobile, Alabama, 36617, United States
Pulmonary Associates
Phoenix, Arizona, 85006, United States
University of Arkansas for Medical Sciences
Little Rock, Arkansas, 72205, United States
Alliance Medical and Research Center
Fountain Valley, California, 92866, United States
Scripps Clinic, Scripps Green Hospital
La Jolla, California, 92037, United States
University of Southern California
Los Angeles, California, 90033, United States
Paloma Medical Group
San Juan Capistrano, California, 92675, United States
Harbor-UCLA Medical Center
Torrance, California, 90502, United States
University of Colorado Denver
Aurora, Colorado, 80045, United States
South Denver Cardiology Associates PC
Littleton, Colorado, 80120, United States
Robert E. Benkert, M.D.P.C.
Wheat Ridge, Colorado, 80033, United States
Lung Health & Sleep Enhancement Center, LLC
Newark, Delaware, 19713, United States
Bay Area Cardiology Research, P.A.
Brandon, Florida, 33511, United States
Bay Area Chest Physicians
Clearwater, Florida, 33756, United States
Broward Pulmonary and Sleep Specialists
Fort Lauderdale, Florida, 33316, United States
Pulmonary Diseases, Internal Medicine, Critical Care Medicine
Fort Lauderdale, Florida, 33334, United States
Mount Sinai Medical Centre - Columbia University - Division of Cardiology
Miami Beach, Florida, 33140, United States
Central Florida Pulmonary Group, PA
Orlando, Florida, 32803, United States
Lung Associates of Sarasota
Sarasota, Florida, 34239, United States
Cleveland Clinic Florida
Weston, Florida, 33331, United States
University of Illinois at Chicago
Chicago, Illinois, 60612, United States
Unity Point Health Pulmonary Services
Peoria, Illinois, 61602, United States
Indiana University
Indianapolis, Indiana, 46202, United States
University of Iowa Hospitals & Clinics
Iowa City, Iowa, 52301, United States
Kentuckiana Pulmonary Associates
Louisville, Kentucky, 40202, United States
University of Louisville School of Medicine
Louisville, Kentucky, 40202, United States
Ochsner Medical Center
New Orleans, Louisiana, 70121, United States
Maine Medical Center
Portland, Maine, 04102, United States
University of Maryland Medical Centre
Baltimore, Maryland, 21201, United States
Johns Hopkins University
Baltimore, Maryland, 21287, United States
University of Michigan Pulmonary Hypertension Program
Ann Arbor, Michigan, 48109, United States
Wayne State University, Detroit Medical Center
Detroit, Michigan, 48324, United States
Spectrum Health
Grand Rapids, Michigan, 49525, United States
William Beaumont Hospital - Troy
Troy, Michigan, 48085, United States
Nebraska Pulmonary Specialties, LLC
Lincoln, Nebraska, 68506, United States
Creighton University Medical Centre - Pulmonary, Critical Care and Sleep Medicine Division
Omaha, Nebraska, 68131, United States
University of Nebraska Medical Center
Omaha, Nebraska, 68198-5300, United States
The Lung Center of Nevada
Las Vegas, Nevada, 89128, United States
Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire, 03756-0001, United States
Michael Schwarz, MDFACC
Bloomfield, New Jersey, 07003, United States
Respiratory Health & Critical Care Associates
Hawthorne, New Jersey, 07506, United States
Pulmonary Hypertension & Lung Transplant Program Newark Beth Israel Medical Center
Newark, New Jersey, 07112, United States
North Shore - LIJ Health System
New Hyde Park, New York, 11040, United States
Beth Israel Medical Center
New York, New York, 10003, United States
Duke University Medical Center
Durham, North Carolina, 27710, United States
East Carolina University
Greenville, North Carolina, 27834, United States
Wake Forest University Phyisicans Clinic/Pulmonary
Winston-Salem, North Carolina, 27157, United States
The Christ Hospital Heart & Vascular Center
Cincinnati, Ohio, 45219, United States
University of Cincinnati Pulmonary Critical Care & Sleep Medicine
Cincinnati, Ohio, 45219, United States
University Hospitals Case Medical Center
Cleveland, Ohio, 44106, United States
Cleveland Clinic
Cleveland, Ohio, 44195, United States
Dayton Respiratory Center
Dayton, Ohio, 45215, United States
University of Toledo Health Sciences Campus
Toledo, Ohio, 43614, United States
Heart Center Cardiology
Bend, Oregon, 97701, United States
Central Bucks Specialists - The Pavilion at Doylestown Hospital
Doylestown, Pennsylvania, 18901, United States
Institute for Respiratory and Sleep Medicine
Langhorne, Pennsylvania, 19007, United States
Pulmonary Hypertension Program, Cardiology, Children's Hospial of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
Pulmonary Vascular Disease Program, Penn Presbyterian Medical Center
Philadelphia, Pennsylvania, 19104, United States
Temple University Hospital
Philadelphia, Pennsylvania, 19140, United States
University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, 15213, United States
Respiratory Specialists
Wyomissing, Pennsylvania, 19610, United States
Wellspan Lung, Sleep and Critical Care
York, Pennsylvania, 17402, United States
Rhode Island Hospital
Providence, Rhode Island, 02903, United States
Medical University of South Carolina
Charleston, South Carolina, 29425, United States
Sioux Falls Cardiovascular PC
Sioux Falls, South Dakota, 57103, United States
Statcare Pulmonary Consultants
Knoxville, Tennessee, 37919, United States
El Paso Respiratory and Sleep Consultants
El Paso, Texas, 79902, United States
University of Texas Medical Branch
Galveston, Texas, 77555, United States
Baylor College of Medicine
Houston, Texas, 77030, United States
UT Health - University of Texas Houston
Houston, Texas, 77030, United States
Providence Health Center
Waco, Texas, 76712, United States
IHVI, Advanced Lung Disease and Transplant Clinic
Falls Church, Virginia, 22042, United States
Sentara Medical Group
Norfolk, Virginia, 23507, United States
Cardiac Study Center
Puyallup, Washington, 98372, United States
PAH Clinic CPR at Auxilio Mutuo
San Juan, 00918, Puerto Rico
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Vallerie McLaughlin, MD
University of Michigan
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Target Duration
- 3 Years
- Sponsor Type
- INDUSTRY
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
July 6, 2011
First Posted
July 8, 2011
Study Start
June 1, 2011
Primary Completion
April 10, 2018
Study Completion
April 10, 2018
Last Updated
August 15, 2018
Record last verified: 2018-08