NCT01385696

Brief Summary

Preference study: Genuair vs HandiHaler inhalers in COPD patients.

Trial Health

90
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
130

participants targeted

Target at P25-P50 for phase_3

Timeline
Completed

Started Jun 2011

Shorter than P25 for phase_3

Geographic Reach
2 countries

4 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2011

Completed
16 days until next milestone

First Submitted

Initial submission to the registry

June 17, 2011

Completed
13 days until next milestone

First Posted

Study publicly available on registry

June 30, 2011

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2012

Completed
1.3 years until next milestone

Results Posted

Study results publicly available

April 22, 2013

Completed
Last Updated

June 24, 2015

Status Verified

May 1, 2015

Enrollment Period

7 months

First QC Date

June 17, 2011

Results QC Date

January 14, 2013

Last Update Submit

May 28, 2015

Conditions

Outcome Measures

Primary Outcomes (1)

  • Percentage of Patients Who Prefer Genuair Device Versus Handihaler Device at Visit 2

    Patients will be asked to answer which device they prefer after 2 weeks of daily practice (visit 2)

    14 days

Secondary Outcomes (2)

  • Mean Overall Satisfaction With Genuair and Handihaler at Visit 2

    14 days

  • Percentage of Patients Making at Least 1 Critical Error Using the Genuair and Handihaler Devices at Visit 2

    14 days

Study Arms (2)

group A

EXPERIMENTAL

Genuair first, HandiHaler second

Device: Genuair® (Almirall S.A.)Device: HandiHaler® (Boehringer Ingelheim's)

group B

EXPERIMENTAL

HandiHaler first, Genuair second

Device: Genuair® (Almirall S.A.)Device: HandiHaler® (Boehringer Ingelheim's)

Interventions

Inhaler with only placebo, once daily, 14 days

group Agroup B

Inhaler with only placebo, once daily, 14 days

group Agroup B

Eligibility Criteria

Age40 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adult male or female patients aged ≥ 40 with stable COPD
  • Naïve patients to the use of study inhalers
  • Patients agreeing on participating and signing the Informed Consent Form

You may not qualify if:

  • Patients with other clinically significant disease, particularly body malformations or diseases affecting coordination and/or motor system
  • Patients unable to read product package instructions and answer patient reported questionnaires

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (4)

Almirall investigative site 3

Bonn, 53119, Germany

Location

Almirall investigative site 5

Koblenz, 56068, Germany

Location

Almirall investigative site 1

Enschede, 7511 JX, Netherlands

Location

Almirall investigative site 2

Zutphen, 7207 AE, Netherlands

Location

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive

Condition Hierarchy (Ancestors)

Lung Diseases, ObstructiveLung DiseasesRespiratory Tract DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and Symptoms

Results Point of Contact

Title
Clinical Project Leader and Trial Manager
Organization
Almirall S.A.

Study Officials

  • Jordi Estruch, Head of GMA

    Almirall, S.A.

    STUDY DIRECTOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
phase 3
Allocation
RANDOMIZED
Masking
NONE
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 17, 2011

First Posted

June 30, 2011

Study Start

June 1, 2011

Primary Completion

January 1, 2012

Study Completion

January 1, 2012

Last Updated

June 24, 2015

Results First Posted

April 22, 2013

Record last verified: 2015-05

Locations