Ultrasound-Guided Needle Biopsy in the Diagnosis of Malignant Cervical Lymphadenopathies

NCT01384357 | Completed

• 1 other identifier: 100026-E
• Study Type: observational
• Target: 116
• Locations: 1 country
• Sites: 1

Brief Summary

The objective of the present study was to compare ultrasound (US) characteristics and ultrasound-guided core-needle biopsy (US-CNB) with US-guided fine-needle aspiration (US-FNA) in the assessment of different malignant cervical lymphadenopathies. Patients with malignant cervical lymphadenopathie with either US-FNA or US-CNB over a 3-year period from 2007 July to 2010 Dec were retrospectively reviewed. There are two major study groups according to the treatment status of the patient's population, including patients who had pathology proofed previous cancer and with clinically cervical lymphadenopathies after treatment. The second group included patients with cervical lymphaenopathies but without previous diagnosis of malignancy and treatment. The results of cytology, or pathology and time of needle biopsy to final diagnosis were traced and recorded. Morphologic US parameters and vascular features were thoroughly evaluated and compared in different disease.

Conditions

Lymphadenopathy; Malignancy

Keywords

lymphadenopathy; needle biopsy; sonography

Outcome Measures

Primary Outcomes (1)

• time of needle biopsy to final diagnosis

  days from needle biopsy to final diagnosis

Study Arms (1)

ultrasound,lymphadenopathy

Eligibility Criteria

• Age: 20 Years - 85 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with malignant cervical lymphadenopathie with either US-FNA or US-CNB over a 3-year period from 2007 July to 2010 Dec were retrospectively reviewed. There are two major study groups according to the treatment status of the patient's population, including patients who had pathology proofed previous cancer and with clinically cervical lymphadenopathies after treatment. The second group included patients with cervical lymphaenopathies but without previous diagnosis of malignancy and treatment.

You may qualify if:

• Patients with malignant cervical lymphadenopathie With US-FNA or US-CNB evaluation before

You may not qualify if:

• No ultrasound exam

Sponsors & Collaborators

• Far Eastern Memorial Hospital: lead

Study Sites (1)

Department of Otolaryngology, Far Eastern Memorial Hospital

Taipei, Taiwan

Location

MeSH Terms

Conditions

Lymphadenopathy; Neoplasms

Condition Hierarchy (Ancestors)

Lymphatic Diseases; Hemic and Lymphatic Diseases

Study Officials

• Li-Jen Liao, M.D.

  Department of Otolaryngology, Far Eastern Memorial Hospital, New Taipei City, Taiwan

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: June 27, 2011
• First Posted: June 29, 2011
• Study Start: July 1, 2007
• Primary Completion: December 1, 2010
• Study Completion: December 1, 2010
• Last Updated: June 29, 2011

Record last verified: 2011-05

Locations

TW (1)