Psoriasis and the Risk of Cardiovascular Disease. A Prospective Study
1 other identifier
observational
100
1 country
2
Brief Summary
There is growing evidence that psoriasis is a systemic disorder which enhances atherosclerosis and the risk of cardiovascular disease. Epidemiological studies have shown an independent association between psoriasis and atherosclerosis, stroke and coronary artery disease. The main goal of this on-going study is to register data which will enable the identification of new markers of atherosclerosis activity and carotid plaque instability in patients with severe psoriasis.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 1, 2011
CompletedFirst Submitted
Initial submission to the registry
June 24, 2011
CompletedFirst Posted
Study publicly available on registry
June 27, 2011
CompletedJune 27, 2011
May 1, 2011
June 24, 2011
June 24, 2011
Conditions
Eligibility Criteria
Patients who have had psoriasis for more than 5 years are being admitted to the study. The assessments include: clinical data, treatment, platelet aggregation and blood viscosity, serum markers and mediators of atherosclerosis, carotid IMT and plaque burden assessed by Color Duplex ultrasound. The patients are recruited from our dermatological department (in and outdoor patients)
You may qualify if:
- \>18 years old, psoriasis for more than 5 years, moderate to severe psoriasis (PASI \>10 or systemic treatment)
You may not qualify if:
- familiar hypercholesterolemia, ongoing infections and cancer disease
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (2)
Dermatological Department, OUS
Oslo, Norway
Oslo university Hospital, Dermatological dept
Oslo, Norway
Biospecimen
blood, tissue
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
June 24, 2011
First Posted
June 27, 2011
Study Start
May 1, 2011
Last Updated
June 27, 2011
Record last verified: 2011-05