Health Benefits of a 21-day Daniel Fast

NCT01378767 | Completed

• 1 other identifier: 110184
• Study Type: interventional
• Target: 39
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators hypothesized that individuals supplementing with krill oil capsules (two grams per day) would experience enhanced improvements in health-related variables during a 21-day Daniel Fast.

Conditions

Effects of Krill Oil on Human Health

Keywords

Dietary restriction; oxidative stress; fasting

Outcome Measures

Primary Outcomes (5)

• Blood Lipids

  Total Cholesterol, LDL-C, HDL-C, VLDL-C, Triglyerides

  Change from baseline at 3 weeks

• Glucoregulatory markers

  Blood glucose, blood insulin, Serum resistin, serum adiponectin

  Change from baseline at 3 weeks

• Markers of Oxidative Stress and Antioxidant Status

  Plasma malondialdehyde, plasma hydrogen peroxide, plasma nitrate/nitrite, Trolox Equivalent Antioxidant Capacity (measured in serum)

  Change from baseline at 3 weeks

• Blood Pressure

  Systolic blood pressure, diastolic blood pressure

  Change from baseline at 3 weeks

• C-reactive protein

  Change from baseline at 3 weeks

Secondary Outcomes (3)

• Anthropometric Variables

  Change from baseline at 3 weeks

• Metabolic Panel

  Change from baseline at 3 weeks

• Complete Blood Count

  Change from baseline at 3 weeks

Study Arms (2)

Krill oil capsules

ACTIVE COMPARATOR

Two grams per day daily for 21 days

Dietary Supplement: Krill oil supplementation

Coconut oil capsules

PLACEBO COMPARATOR

Two grams per day for 21 days

Dietary Supplement: Krill oil supplementation

Interventions

Krill oil supplementation DIETARY_SUPPLEMENT

During a 21-day Daniel Fast, group one supplemented with krill oil capsules (two grams per day) while group two supplemented with a placebo (coconut oil capsules at two grams per day).

Also known as: Now Foods Neptune Krill Oil, 1000 mg- 60 Soft Gels, Brand NOW, Part Numbers 14431, 1627, 82048, NOW-01627, NWF-16270, NWF622, UPC 733739016270, Now Foods Coconut Oil, 1000 mg- 120 Soft Gels, Part Numbers 091363-2, 1718, 18918, 24230, 5933510, 6485, 71668, 806542, NWF-17185, NWF119, UPC 733739017185

Coconut oil capsules; Krill oil capsules

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Must be 18 years of age or older.
• Must be willing to partake in a vegan diet for 21 days.
• Must be willing to consume either krill oil or coconut oil capsules (assigned randomly).

You may not qualify if:

• Smokers
• regular consumption of antioxidant supplements
• women who were pregnant or seeking to become pregnant
• poor veins (veins that made it difficult to successfully obtain a blood draw - this was determined via a visual inspection)

Sponsors & Collaborators

• University of Memphis: lead

Study Sites (1)

Cardiorespiratory/Metabolic Laboratory

Memphis, Tennessee, 38152, United States

Location

Related Publications (1)

• Trepanowski JF, Kabir MM, Alleman RJ Jr, Bloomer RJ. A 21-day Daniel fast with or without krill oil supplementation improves anthropometric parameters and the cardiometabolic profile in men and women. Nutr Metab (Lond). 2012 Sep 13;9(1):82. doi: 10.1186/1743-7075-9-82.

  PMID: 22971786 DERIVED

MeSH Terms

Conditions

Fasting

Condition Hierarchy (Ancestors)

Feeding Behavior; Behavior

Study Officials

• Richard J Bloomer, Doctorate

  University of Memphis

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: QUADRUPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER

Study Record Dates

• First Submitted: June 10, 2011
• First Posted: June 22, 2011
• Study Start: September 1, 2010
• Primary Completion: December 1, 2010
• Study Completion: December 1, 2010
• Last Updated: June 22, 2011

Record last verified: 2011-06

Locations

US (1)