ED50 of Dexmedetomidine to Prevent Emergence Agitation in Children
ED50 of Dexmedetomidine for Reduction of Emergence Agitation Incidence Undergoing Tonsillectomy or Adenoidectomy in Desflurane Anesthesia Following Sevoflurane Induction in Children
1 other identifier
interventional
25
1 country
1
Brief Summary
There are several recommended doses of dexmedetomidine for prevention of emergence agitation in children. In this study, the investigators examine ED50 in prevention of emergence agitation after tonsillectomy or adenoidectomy in children.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for phase_4
Started Jun 2011
Shorter than P25 for phase_4
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 1, 2011
CompletedFirst Submitted
Initial submission to the registry
June 9, 2011
CompletedFirst Posted
Study publicly available on registry
June 16, 2011
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2011
CompletedStudy Completion
Last participant's last visit for all outcomes
February 1, 2012
CompletedJune 16, 2011
June 1, 2011
6 months
June 9, 2011
June 15, 2011
Conditions
Outcome Measures
Primary Outcomes (1)
agitation
30 minutes
Secondary Outcomes (1)
pain
30 minutes
Study Arms (1)
dexmedetomidine, children
OTHERInterventions
dexmedetomidine, 0.1ug/kg up or down
Eligibility Criteria
You may qualify if:
- tonsillectomy or adenoidectomy
You may not qualify if:
- recent URI
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
SNUH
Seoul, 110744, South Korea
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Hee-Soo Kim, M.D, PhD
Seoul National University Hospital
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- phase 4
- Allocation
- NON RANDOMIZED
- Masking
- QUADRUPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- PREVENTION
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
June 9, 2011
First Posted
June 16, 2011
Study Start
June 1, 2011
Primary Completion
December 1, 2011
Study Completion
February 1, 2012
Last Updated
June 16, 2011
Record last verified: 2011-06