NCT01362660

Brief Summary

This study will examine post-natal neurologic and cognitive development of infants who may have been exposed to tanezumab or comparator in-utero during the tanezumab clinical program (whether the exposure is through maternal or paternal participation in a tanezumab clinical study).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
7

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Jun 2011

Shorter than P25 for all trials

Geographic Reach
1 country

8 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 24, 2011

Completed
6 days until next milestone

First Posted

Study publicly available on registry

May 30, 2011

Completed
2 days until next milestone

Study Start

First participant enrolled

June 1, 2011

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2012

Completed
Last Updated

February 6, 2013

Status Verified

February 1, 2013

Enrollment Period

1 year

First QC Date

May 24, 2011

Last Update Submit

February 5, 2013

Conditions

Keywords

post-natal monitoringexposure in utero

Outcome Measures

Primary Outcomes (6)

  • Bayley Infant Neurodevelopmental Screener

    0-2 Months

  • Bayley Infant Neurodevelopmental Screener

    8 months

  • Bayley Infant Neurodevelopmental Screener

    15 months

  • Receptive-Expressive Emergent Language Test

    0-2 Months

  • Receptive-Expressive Emergent Language Test

    8 months

  • Receptive-Expressive Emergent Language Test

    15 months

Study Arms (1)

Infants with potential exposure in utero

Other: Unintentional exposure in utero

Interventions

This study will examine post-natal neurologic and cognitive development of infants who may have been exposed to tanezumab or comparator in-utero during the tanezumab clinical program (whether the exposure is through maternal or paternal participation in a tanezumab clinical study).

Infants with potential exposure in utero

Eligibility Criteria

AgeUp to 15 Months
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

Infants with potential exposure in utero through their parents partcipation in a tanezumab clinical study

You may qualify if:

  • Subject is an infant born to a mother who was exposed to study drug on a tanezumab clinical study through direct maternal exposure; or is an infant born to a mother who is a partner of a male patient who was exposed to study drug in a tanezumab clinical study prior to or around the time of conception and/or is exposed during his partner's pregnancy.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (8)

Pfizer Investigational Site

Tempe, Arizona, 85282, United States

Location

Pfizer Investigational Site

Tempe, Arizona, 85283, United States

Location

Pfizer Investigational Site

Wildomar, California, 92595, United States

Location

Pfizer Investigational Site

Cutler Bay, Florida, 33189, United States

Location

Pfizer Investigational Site

Duncansville, Pennsylvania, 16635, United States

Location

Pfizer Investigational Site

Memphis, Tennessee, 38119-5214, United States

Location

Pfizer Investigational Site

Houston, Texas, 77065, United States

Location

Pfizer Investigational Site

Salt Lake City, Utah, 84109, United States

Location

Related Links

Study Officials

  • Pfizer CT.gov Call Center

    Pfizer

    STUDY DIRECTOR

Study Design

Study Type
observational
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 24, 2011

First Posted

May 30, 2011

Study Start

June 1, 2011

Primary Completion

June 1, 2012

Study Completion

June 1, 2012

Last Updated

February 6, 2013

Record last verified: 2013-02

Locations