Optic Nerve and Retinal Functions With Bevacizumab
Electrophysiological Assessment of Optic Nerve and Retinal Functions Following Intravitreal Injection of Bevacizumab (Avastin).
1 other identifier
observational
45
1 country
1
Brief Summary
The purpose of this study is to investigate the possible affection of optic nerve and retinal functions following intravitreal bevacizumab injection in human eyes.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for all trials
Started Jan 2010
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 1, 2010
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 1, 2010
CompletedStudy Completion
Last participant's last visit for all outcomes
July 1, 2010
CompletedFirst Submitted
Initial submission to the registry
May 26, 2011
CompletedFirst Posted
Study publicly available on registry
May 27, 2011
CompletedMay 27, 2011
January 1, 2010
6 months
May 26, 2011
May 26, 2011
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Visual Evoked Potential and Electroretinogram
VEP and ERG baseline and at 1 and 4 weeks post intravitreal injection of bevacizumab.
4 weeks
Study Arms (1)
Patients with choroidal neovascularization
CNV due to Age-Related Macular Degenerations and Myopia were included.
Interventions
Visual Evoked Potential and Elctroretinogram
Eligibility Criteria
Forty five eyes of 45 patients with choroidal neovascular membrane (CNV) who were prepared for intravitreal injections of 1.25mg bevacizumab underwent baseline ERG and VEP in both eyes before, and at 1 and 4 weeks after the intravitreal injections.Mean age was 50 years ranging from 24-62 years with 25 females, with 28 AMD and 17 myopic patients.
You may qualify if:
- CNV
You may not qualify if:
- Previous Intravitreal Injections
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Cairo Universitylead
Study Sites (1)
Cairo University
Cairo, --- Select One ---, 11421, Egypt
Related Links
Study Officials
- PRINCIPAL INVESTIGATOR
Tamer A macky
Cairo University
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
Study Record Dates
First Submitted
May 26, 2011
First Posted
May 27, 2011
Study Start
January 1, 2010
Primary Completion
July 1, 2010
Study Completion
July 1, 2010
Last Updated
May 27, 2011
Record last verified: 2010-01