NCT01355653

Brief Summary

This study is designed to compare the safety, as measured by skin findings and adverse events, of two different heat devices in elderly, overweight, and elderly and overweight subjects.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
45

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started May 2011

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 28, 2011

Completed
7 days until next milestone

Study Start

First participant enrolled

May 5, 2011

Completed
13 days until next milestone

First Posted

Study publicly available on registry

May 18, 2011

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 28, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 28, 2011

Completed
Last Updated

July 2, 2025

Status Verified

June 1, 2025

Enrollment Period

3 months

First QC Date

April 28, 2011

Last Update Submit

June 25, 2025

Conditions

Keywords

heatdevicesafetyperformanceheatwrapelderlyoverweight

Outcome Measures

Primary Outcomes (1)

  • Percentage of subjects with any thermal-related skin events (defined as elevated skin response, erythema ≥ 2.0 [moderate], or pain upon touch plus non-zero erythema)

    morning after product wear through 15 days after last product application

Secondary Outcomes (1)

  • Percentage of subjects with any adverse event

    during and after wear for 28 days after last wear

Study Arms (2)

Treatment A

EXPERIMENTAL

thermal therapy

Device: thermal therapy

Treatment B

ACTIVE COMPARATOR

ThermaCare Lower Back/Hip heatwrap

Device: ThermaCare heatwrap

Interventions

heat therapy device, topical, two applications, at 0-3 hours and 4-6 hours on treatment day

Treatment A

heatwrap, topical, one time application, 8 hour duration

Treatment B

Eligibility Criteria

Age18 Years - 84 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Males or females in generally good health, and who are either 18-54 years of age with a body mass index of ≥ 30 kg/m2
  • or 55-84 years of age and with a body mass index ≥ 30 kg/m2 or \< 30 kg/m2
  • Females who are not pregnant or breastfeeding
  • Subject is medically cleared for study participation

You may not qualify if:

  • No sensitivitiy or allergy to device components in contact with skin
  • Diabetes
  • Any active skin disease or tattoos at the test site that would affect participation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Loma Linda University

Loma Linda, California, 92350, United States

Location

Related Links

MeSH Terms

Conditions

Back PainOverweight

Condition Hierarchy (Ancestors)

PainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and SymptomsOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody Weight

Study Officials

  • Pfizer CT.gov Call Center

    Pfizer

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
OTHER
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 28, 2011

First Posted

May 18, 2011

Study Start

May 5, 2011

Primary Completion

July 28, 2011

Study Completion

July 28, 2011

Last Updated

July 2, 2025

Record last verified: 2025-06

Data Sharing

IPD Sharing
Will not share

Locations