Epidemiologic Follow Up Study of Newly Diagnosed Epilepsy Among Seniors

NCT01351727 | Completed

• 1 other identifier: 10-0916-01
• Study Type: observational
• Target: 97
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this proposed research is to identify individuals in southeastern Arizona aged 65 years and older who have new onset seizures (or newly diagnosed epilepsy) and monitor them for at least two years. In doing so the investigators will be able to describe the public health burden of this condition and to identify factors that predict clinical outcomes and health care needs in this population, using quantitative, administrative, and qualitative data. The aims of this proposed research are 1) to determine the two-year incidence of newly diagnosed epilepsy in the target population, 2) describe health care resource utilization of the target population using Medicare data, 3) validate the use of Medicare beneficiary data to estimate incidence of epilepsy, and 4) describe the burden of this condition in different ethnic groups.

Conditions

Epileptic Seizures

Keywords

seniors; seizures; epilepsy; quality of life

Outcome Measures

Primary Outcomes (1)

• A two-year incidence rate of new-onset seizures and/or newly-diagnosed epilepsy among seniors in southeastern Arizona.

  A surveillance mechanism will be developed to identify and recruit seniors from emergency departments, neurology clinics, primary care clinics, and other service providers for seniors.

  Up to four years

Secondary Outcomes (1)

• Compare the impact of epilepsy on the different ethnic groups of seniors with epilepsy

  Up to four years

Study Arms (1)

Seniors with Seizures

Seniors aged 65 or older with newly diagnosed seizures (consistent with epilepsy) or epilepsy as of October, 2010.

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Hospitals (including emergency departments), neurology specialist clinics, primary care clinics, communities (in Cochise, Pima, Santa Cruz Counties)including nursing homes, skilled nursing facilities, assisted living facilities.

You may qualify if:

• Aged 65 years or older
• New onset seizure or newly diagnosed epilepsy as of October 2010
• Is a resident of Pima, Cochise or Santa Cruz County

You may not qualify if:

• Seizure dues to hyponatremia, hypoglycemia, alcohol use (with no evidence of other seizures)

Sponsors & Collaborators

• University of Arizona: lead
• Centers for Disease Control and Prevention: collaborator

Study Sites (1)

Pima, Cochise, Santa Cruz Counties

Tucson, Arizona, 85724, United States

Location

Related Publications (3)

• Martin R, Vogtle L, Gilliam F, Faught E. What are the concerns of older adults living with epilepsy? Epilepsy Behav. 2005 Sep;7(2):297-300. doi: 10.1016/j.yebeh.2005.05.003.

  PMID: 15996527 BACKGROUND

• Pallin DJ, Goldstein JN, Moussally JS, Pelletier AJ, Green AR, Camargo CA Jr. Seizure visits in US emergency departments: epidemiology and potential disparities in care. Int J Emerg Med. 2008 Jun;1(2):97-105. doi: 10.1007/s12245-008-0024-4. Epub 2008 Jun 5.

  PMID: 19384659 BACKGROUND

• Tallis R, Hall G, Craig I, Dean A. How common are epileptic seizures in old age? Age Ageing. 1991 Nov;20(6):442-8. doi: 10.1093/ageing/20.6.442.

  PMID: 1776595 BACKGROUND

MeSH Terms

Conditions

Seizures; Epilepsy

Condition Hierarchy (Ancestors)

Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Brain Diseases; Central Nervous System Diseases

Study Officials

• David Labiner, MD

  University of Arizona

  PRINCIPAL INVESTIGATOR

• Jenny Chong, PhD

  University of Arizona

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Research Associate Professor

Study Record Dates

• First Submitted: May 9, 2011
• First Posted: May 11, 2011
• Study Start: January 1, 2011
• Primary Completion: September 1, 2014
• Study Completion: September 1, 2014
• Last Updated: November 6, 2017

Record last verified: 2017-11

Locations

US (1)