NCT01346631

Brief Summary

Prospective studies concerning diet and male fertility are lacking. Observational studies suggest that a diet rich in fruits, vegetables and meats may be associated with higher sperm counts. The investigators wanted to see if a "paleolithic diet" consisting of meat, fish, fruits vegetables and nuts and lacking grains, legumes and dairy products can improve sperm counts.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started May 2011

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 1, 2011

Completed
Same day until next milestone

Study Start

First participant enrolled

May 1, 2011

Completed
2 days until next milestone

First Posted

Study publicly available on registry

May 3, 2011

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2012

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2012

Completed
Last Updated

June 23, 2015

Status Verified

June 1, 2015

Enrollment Period

1 year

First QC Date

May 1, 2011

Last Update Submit

June 21, 2015

Conditions

Outcome Measures

Primary Outcomes (1)

  • Sperm Parameters

    volume, concentration, motility, morphology

    3 months

Secondary Outcomes (1)

  • Biomedical Indexes

    3 months

Study Arms (1)

paleolithic diet

EXPERIMENTAL

Subjects will adhere to a paleolithic diet for the duration of three months

Other: paleolithic diet

Interventions

The diet consists of unlimited quantities of meat and fish, fruits and vegetables, eggs, nuts and water. Foods to be avoided include grains, wheat products, legumes, soy, potatoes and corn, rice, legumes, processed meats, soft drinks, dairy products and sugar. Allowed in moderation include coffee, alcohol,cooking oil, honey, salt, dried fruit.

paleolithic diet

Eligibility Criteria

Age18 Months+
Sexmale
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • men with male infertility
  • willingness to make dietary change for three months
  • willingness to be blinded to sperm test results until the end of the experiment

You may not qualify if:

  • High fever or abdominal or scrotal surgery during three months prior to intervention
  • Change in diet, drinking or smoking habits in three months prior to intervention
  • regular consumption of more than two servings of alcohol a day
  • background ailment preventing dietary change

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

HaEmek Medical Center

Afula, Israel

Location

MeSH Terms

Conditions

Infertility, Male

Interventions

Diet, Paleolithic

Condition Hierarchy (Ancestors)

Genital Diseases, MaleGenital DiseasesUrogenital DiseasesInfertilityMale Urogenital Diseases

Intervention Hierarchy (Ancestors)

Diet TherapyNutrition TherapyTherapeuticsDietNutritional Physiological PhenomenaDiet, Food, and NutritionPhysiological Phenomena
0

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER

Study Record Dates

First Submitted

May 1, 2011

First Posted

May 3, 2011

Study Start

May 1, 2011

Primary Completion

May 1, 2012

Study Completion

May 1, 2012

Last Updated

June 23, 2015

Record last verified: 2015-06

Locations