NCT01345396

Brief Summary

Asthma is the most frequent respiratory disease during pregnancy. In a third of cases, the level of asthma control can decrease during the pregnancy, especially between the 29th and the 36th week. The occurrence of such complications are linked with a high asthma severity level just before the conception and an history of respiratory complications in a previous pregnancy. Many reviews and recommendations claim that pregnant women with asthma should be included in an educational progamme. However, this is poorly studied. The purpose of this study is to observe if an educational programme given before the 20th weeks of gestation has an effect on asthma control until the end of gestation.

Trial Health

33
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Trial recruitment is currently suspended
Enrollment
80

participants targeted

Target at P50-P75 for not_applicable asthma

Timeline
Completed

Started Feb 2010

Longer than P75 for not_applicable asthma

Geographic Reach
1 country

1 active site

Status
suspended

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2010

Completed
1.2 years until next milestone

First Submitted

Initial submission to the registry

April 28, 2011

Completed
4 days until next milestone

First Posted

Study publicly available on registry

May 2, 2011

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2013

Completed
2.8 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2015

Completed
Last Updated

April 4, 2019

Status Verified

April 1, 2019

Enrollment Period

3 years

First QC Date

April 28, 2011

Last Update Submit

April 3, 2019

Conditions

Keywords

AsthmaHealth educationPregnancy

Outcome Measures

Primary Outcomes (1)

  • The level of asthma control

    Assessment by the Asthma Control Questionnaire

    Inclusion (baseline), 36 weeks of gestation, 12 weeks post partum

Secondary Outcomes (3)

  • Number of unscheduled visits to the doctor for asthma

    Inclusion (baseline), 36 weeks of gestation, 12 weeks post partum

  • Quality of life

    Inclusion (baseline), 36 weeks of gestation, 12 weeks post partum

  • Knowledge about asthma

    Inclusion (baseline), 36 weeks of gestation, 12 weeks post partum

Study Arms (2)

Education

EXPERIMENTAL
Behavioral: Health education about asthma

No education

NO INTERVENTION

Interventions

Three face-to-face appointments (\<20, 36 weeks of gestation and 12 weeks after the baby birth). Topics: What is asthma? What influence the course of asthma? How to monitor it? How to manage it?

Education

Eligibility Criteria

Age18 Years - 40 Years
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • Diagnosis of asthma before the pregnancy (clinical history and specific medications used)
  • Agreement to enter into the study

You may not qualify if:

  • History of major respiratory problems during previous pregnancy(ies)
  • Refusal to enter into the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHU St Pierre; pulmonology department

Brussels, Belgium

Location

MeSH Terms

Conditions

AsthmaHealth Education

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System DiseasesAdherence InterventionsMedication AdherencePatient CompliancePatient Acceptance of Health CareTreatment Adherence and ComplianceHealth BehaviorBehavior

Study Officials

  • Vincent Ninane, MD PhD

    CHU St Pierre Brussels

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Prof. Dr. V. Ninane

Study Record Dates

First Submitted

April 28, 2011

First Posted

May 2, 2011

Study Start

February 1, 2010

Primary Completion

February 1, 2013

Study Completion

December 1, 2015

Last Updated

April 4, 2019

Record last verified: 2019-04

Locations