NCT01343160

Brief Summary

The purpose of this study is to generate clinical data to support the use of GORE® VIABIL® Biliary Endoprosthesis in the endoscopic and percutaneous treatment of benign biliary strictures.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
43

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Apr 2011

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 14, 2011

Completed
2 months until next milestone

Study Start

First participant enrolled

April 1, 2011

Completed
26 days until next milestone

First Posted

Study publicly available on registry

April 27, 2011

Completed
4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2015

Completed
6 years until next milestone

Results Posted

Study results publicly available

April 21, 2021

Completed
Last Updated

April 21, 2021

Status Verified

March 1, 2021

Enrollment Period

4.1 years

First QC Date

February 14, 2011

Results QC Date

March 25, 2021

Last Update Submit

March 25, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Safe Stent Removal

    The stent removal is considered safe when the Study Device is removed successfully and without SAEs.

    Upon Removal

Other Outcomes (7)

  • Primary Device Patency

    12 Months

  • Successful Delivery and Deployment

    Upon Implant

  • Successful Treatment of Benign Stricture Upon Implant

    Upon implant

  • +4 more other outcomes

Study Arms (1)

GORE VIABIL® Biliary Endoprosthesis

OTHER

Placement of GORE VIABIL® Biliary Endoprosthesis to establish duct patency

Device: GORE® VIABIL® Biliary Endoprosthesis

Interventions

Deployment of GORE® VIABIL® Biliary Endoprosthesis to the area of stricture

GORE VIABIL® Biliary Endoprosthesis

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Subject is diagnosed with treatable benign biliary stricture which necessitates the need for implantation of a biliary endoprosthesis
  • Subject is ≥18 years of age
  • Subject is able to comply with study protocol and follow-up requirements
  • Written informed consent is obtained using the Investigational Review Board (IRB)/Ethics Committee (EC) approved consent form

You may not qualify if:

  • Subject anatomy ruling out covered self expanding metal stent use (e.g. above hilar region)
  • Treatment of stricture would require placement of a covered biliary endoprosthesis within a previously placed bare metal stent
  • The subject has malignant biliary disease
  • Subject has known pregnancy
  • Participated in protocol involving investigational drug or device within 90 days prior to entry into this study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Klinikum Ludwigsburg

Ludwigsburg, Germany

Location

Results Point of Contact

Title
Rizwan Afzal
Organization
W.L. Gore & Associates

Study Officials

  • Karel Caca, MD

    Klinikum Ludwigsburg

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 14, 2011

First Posted

April 27, 2011

Study Start

April 1, 2011

Primary Completion

May 1, 2015

Study Completion

May 1, 2015

Last Updated

April 21, 2021

Results First Posted

April 21, 2021

Record last verified: 2021-03

Locations