NCT01339585

Brief Summary

This project will investigate a novel strategy for enhancing cognitive training (CT). Specifically, the investigators aim to combine a non-invasive form of brain stimulation (tDCS) with CT. This study will examine the optimal time interval - whether tDCS should be administered either before or during CT.

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 1, 2011

Completed
19 days until next milestone

First Posted

Study publicly available on registry

April 20, 2011

Completed
11 days until next milestone

Study Start

First participant enrolled

May 1, 2011

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2014

Completed
Last Updated

August 12, 2014

Status Verified

August 1, 2014

Enrollment Period

3 years

First QC Date

April 1, 2011

Last Update Submit

August 11, 2014

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change in performance across each condition.

    D prime, number of correct responses, and number of errors.

    Over 2 days, with each condition conducted 1 month apart.

Study Arms (2)

Timing of tDCS

EXPERIMENTAL
Device: Transcranial direct current stimulation (tDCS)

Alternative timing of tDCS

EXPERIMENTAL
Device: Transcranial direct current stimulation (tDCS)

Interventions

Eldith Direct Current Stimulator (NeuroConn GmbH, Germany)

Alternative timing of tDCSTiming of tDCS

Eligibility Criteria

Age18 Years - 40 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Participants will be healthy right-handed subjects aged 18 to 40 years.

You may not qualify if:

  • Concurrent medication likely to affect mental performance,
  • Current history of drug or alcohol abuse or dependence,
  • Any psychiatric or neurological disorder,
  • Recent head injury, or history of seizure or stroke.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

School of Psychiatry

Sydney, New South Wales, Australia

Location

MeSH Terms

Interventions

Transcranial Direct Current Stimulation

Intervention Hierarchy (Ancestors)

Electric Stimulation TherapyTherapeuticsConvulsive TherapyPsychiatric Somatic TherapiesBehavioral Disciplines and ActivitiesElectroshockPsychological Techniques

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
BASIC SCIENCE
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Research Assistant

Study Record Dates

First Submitted

April 1, 2011

First Posted

April 20, 2011

Study Start

May 1, 2011

Primary Completion

May 1, 2014

Last Updated

August 12, 2014

Record last verified: 2014-08

Locations