NCT01333800

Brief Summary

The Objective was to Develop a Cost-Effectiveness study that compares Ciclesonide and Beclomethasone in pediatric asthma control.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
94

participants targeted

Target at P50-P75 for phase_4 asthma

Timeline
Completed

Started Jul 2010

Shorter than P25 for phase_4 asthma

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2010

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2010

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

April 8, 2011

Completed
4 days until next milestone

First Posted

Study publicly available on registry

April 12, 2011

Completed
Last Updated

April 12, 2011

Status Verified

April 1, 2011

Enrollment Period

5 months

First QC Date

April 8, 2011

Last Update Submit

April 11, 2011

Conditions

Outcome Measures

Primary Outcomes (1)

  • Effectiveness measured as number of patients free of asthmatic crisis with each molecule during the study period

    Effectiveness was assesed counting number of patients that were free of asthmatic crisis for each steroid ciclesonide and beclomethasone during 6 months of treatment

    6 months

Study Arms (2)

Ciclesonide

ACTIVE COMPARATOR
Drug: Ciclesonide

Beclomethasone

PLACEBO COMPARATOR
Drug: Beclomethasone

Interventions

200 to 400 mcg per day for 6 months

Beclomethasone

80 to 160 mcg per day for 6 months

Ciclesonide

Eligibility Criteria

Age6 Years - 15 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)

You may qualify if:

  • Patients with uncontrolled asthma diagnosis
  • Patients with only one controller medication

You may not qualify if:

  • Patients without lung infection
  • Patients without antibiotic use

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hospital San Rafael

Bogotá, 11001000, Colombia

Location

MeSH Terms

Conditions

Asthma

Interventions

Beclomethasoneciclesonide

Condition Hierarchy (Ancestors)

Bronchial DiseasesRespiratory Tract DiseasesLung Diseases, ObstructiveLung DiseasesRespiratory HypersensitivityHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Intervention Hierarchy (Ancestors)

PregnadienetriolsPregnadienesPregnanesSteroidsFused-Ring CompoundsPolycyclic CompoundsSteroids, Chlorinated

Study Officials

  • Francisco Hinestrosa, MD,MSc

    Grünenthal Colombiana S.A.

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 4
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY

Study Record Dates

First Submitted

April 8, 2011

First Posted

April 12, 2011

Study Start

July 1, 2010

Primary Completion

December 1, 2010

Study Completion

December 1, 2010

Last Updated

April 12, 2011

Record last verified: 2011-04

Locations