NCT01329419

Brief Summary

An open label, multi-centre, non-interventional post-marketing surveillance to monitor the safety and/or efficacy of adefovir dipivoxil administered in Korean CHB patients according to the prescribing information

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
4,393

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Aug 2004

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2004

Completed
5.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2010

Completed
1.1 years until next milestone

First Submitted

Initial submission to the registry

March 10, 2011

Completed
26 days until next milestone

First Posted

Study publicly available on registry

April 5, 2011

Completed
Same day until next milestone

Results Posted

Study results publicly available

April 5, 2011

Completed
Last Updated

July 5, 2017

Status Verified

June 1, 2017

Enrollment Period

5.5 years

First QC Date

March 10, 2011

Results QC Date

March 10, 2011

Last Update Submit

June 6, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Number of Participants With an Adverse Event

    An adverse event (AE) is any untoward medical occurrence in a participant, temporally associated with the use of a medicinal product, whether or not considered related to the medicinal product. For a list of all adverse events occurring during the course of the study, please see the table entitled "Other (non-serious) adverse events" in the Adverse Event section of the results record.

    12 weeks

Secondary Outcomes (2)

  • Number of Participants With a Serious Adverse Event

    12 weeks

  • Number of Participants With the Indicated Unexpected Adverse Events

    12 weeks

Study Arms (1)

adefovir dipivoxil

Patients administrated adefovir at the site

Drug: adefovir dipivoxil

Interventions

Basically there is no treatment allocation. Subjects who would be administered of adefovir at their physicians' discretion will be enrolled. Dosage regimen will be recommended according to the prescribing information. Subjects will be enrolled consecutively.

adefovir dipivoxil

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients administrated adefovir dipivoxil at the site

You may qualify if:

  • Patients administrated adefovir dipivoxil at the site

You may not qualify if:

  • Patients administrated adefovir dipivoxil before center initiated date

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Hepatitis B

Interventions

adefovir dipivoxil

Condition Hierarchy (Ancestors)

Blood-Borne InfectionsCommunicable DiseasesInfectionsHepadnaviridae InfectionsDNA Virus InfectionsVirus DiseasesHepatitis, Viral, HumanHepatitisLiver DiseasesDigestive System Diseases

Results Point of Contact

Title
GSK Response Center
Organization
GlaxoSmithKline

Study Officials

  • GSK Clinical Trials

    GlaxoSmithKline

    STUDY DIRECTOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 10, 2011

First Posted

April 5, 2011

Study Start

August 1, 2004

Primary Completion

February 1, 2010

Study Completion

February 1, 2010

Last Updated

July 5, 2017

Results First Posted

April 5, 2011

Record last verified: 2017-06