Brief Summary

The purpose of this study is to study the HIV disease progression in HIV-infected Thai Adult.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
5,600

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Dec 2007

Longer than P75 for all trials

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2007

Completed
3.3 years until next milestone

First Submitted

Initial submission to the registry

March 2, 2011

Completed
1 month until next milestone

First Posted

Study publicly available on registry

April 4, 2011

Completed
4.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2015

Completed
Last Updated

May 11, 2016

Status Verified

May 1, 2016

Enrollment Period

7.5 years

First QC Date

March 2, 2011

Last Update Submit

May 9, 2016

Conditions

Keywords

HIV related adverse eventsimmunological failurevirological failurequality of lifedepressiongenotypic resistance

Outcome Measures

Primary Outcomes (1)

  • HIV related adverse events

    Time until patient has HIV related adverse events

    1 year

Secondary Outcomes (5)

  • Immunological failure

    1 year

  • virological failure

    1 year

  • the change of quality of life

    1 year

  • depression

    1 year

  • genotypic resistance

    1 year

Study Arms (1)

1

long-term follow-up of HIV-infected patients on ART

Drug: standard regimens according to the Thai Ministry of Public Health national guidelines

Interventions

Participants may receive any of the standard regimens. These regimens are recommended in the Thai Ministry of Public Health National guidelines for the treatment of HIV in children. Change of treatment will be according to the treating physicians.

1

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

HIV-infected patients currently receiving ART at Bamrasnaradura Institute, Sanpatong Hospital or HIV-NAT, Thai Red Cross AIDS Research Centre, Bangkok.

You may qualify if:

  • There is evidence that HIV infection true (blood positive results by ELISA (ELISA) has been confirmed or detected evidence co-infection. HIV in the body by PCR, HIV-RNA PCR).Currently on PI regimens
  • Signed consent form
  • Age\> 18 years

You may not qualify if:

  • Patients who came for treatment in a department other than out patient, such as inpatient or emergency room.
  • Patients are not willing to receive treatment on a regular basis in all 3 hospitals as patients normally receive treatment at other hospitals on a regular basis. However, due to urgent events. Need to receive treatment in hospital and three of.
  • Patients who have been diagnosed by doctors as a Psychological disorder that can not store the data.
  • Patients who have been diagnosed by a medical condition that Alcoholism

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Bamrasnaradura infectious disease institute

Nonthaburi, Changwat Nonthaburi, 11000, Thailand

Location

Sanpatong Hospital

Chiang Mai, Chiang Mai, Thailand

Location

HIV-NAT, Thai Red Cross AIDS Research Centre

Bangkok, 10330, Thailand

Location

Related Publications (1)

  • Pongpirul W, Pongpirul K, Ananworanich J, Klinbuayaem V, Avihingsanon A, Prasithsirikul W. Chronic kidney disease incidence and survival of Thai HIV-infected patients. AIDS. 2018 Jan 28;32(3):393-398. doi: 10.1097/QAD.0000000000001698.

Related Links

Biospecimen

Retention: SAMPLES WITH DNA

serum

MeSH Terms

Conditions

Depression

Condition Hierarchy (Ancestors)

Behavioral SymptomsBehavior

Study Officials

  • Wisit Prasithsirikul, MD

    Bamrasnaradura infectious disease institute

    PRINCIPAL INVESTIGATOR
  • Wirat Klinbuayam, MD

    Sanpatong Hospital

    PRINCIPAL INVESTIGATOR
  • Jintanat Ananworanich, MD, PhD

    HIV-NAT, Thai Red Cross - AIDS Research Centre

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

March 2, 2011

First Posted

April 4, 2011

Study Start

December 1, 2007

Primary Completion

June 1, 2015

Study Completion

June 1, 2015

Last Updated

May 11, 2016

Record last verified: 2016-05

Locations