Treatment of Acne Keloidalis Nuchae (Razor Bumps Behind the Neck) Using UV Light Therapy
Improving Acne Keloidalis Nuchae by Inducing Matrix Metalloproteinases in Vivo Using Targeted Ultraviolet-B Irradiation
1 other identifier
interventional
11
1 country
1
Brief Summary
This study is being done to evaluate the effect of targeted UV-B (a component of sunlight) on the treatment of acne keloidalis nuchae (AKN, or razor bumps on the back of the neck). The investigators believe targeted UV-B is a safe and effective way to reduce the appearance of AKN.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Feb 2011
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2011
CompletedFirst Submitted
Initial submission to the registry
March 31, 2011
CompletedFirst Posted
Study publicly available on registry
April 4, 2011
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2012
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2012
CompletedResults Posted
Study results publicly available
June 16, 2014
CompletedMarch 29, 2017
February 1, 2017
1.5 years
March 31, 2011
April 21, 2014
February 28, 2017
Conditions
Outcome Measures
Primary Outcomes (1)
Percentage Change in Total AKN Lesions From Baseline to Week 16.
To determine if treatment of AKN with targeted ultraviolet B radiation will improve the clinical appearance of lesions.
Baseline to Week 16
Study Arms (2)
Targeted UV-B (Left)
EXPERIMENTALTargeted UV-B on left side of the scalp.
Targeted UV-B (Right)
EXPERIMENTALTargeted UV-B on right side of the scalp.
Interventions
Daavlin Lumera phototherapy device (290-320 nm), dosed by patients' individual minimal erythema dose (MED)
Eligibility Criteria
You may qualify if:
- age 18 or over
- male gender
- African-American or other black ethnicity
- current diagnosis of acne keloidalis nuchae (razor bumps on back of neck)
You may not qualify if:
- allergy to lidocaine or numbing medicine
- history of increased sensitivity to sunlight, lupus, or porphyria
- current use of a drug that increases sensitivity to sunlight
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Johns Hopkins Universitylead
- Skin of Color Societycollaborator
Study Sites (1)
Johns Hopkins Dept. of Dermatology
Baltimore, Maryland, 21287, United States
Related Links
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Results Point of Contact
- Title
- Ginette Okoye, MD, Director of Ethnic Skin Program
- Organization
- Johns Hopkins Dermatology
Publication Agreements
- PI is Sponsor Employee
- No
- Restrictive Agreement
- No
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- INVESTIGATOR
- Purpose
- TREATMENT
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant Professor
Study Record Dates
First Submitted
March 31, 2011
First Posted
April 4, 2011
Study Start
February 1, 2011
Primary Completion
August 1, 2012
Study Completion
August 1, 2012
Last Updated
March 29, 2017
Results First Posted
June 16, 2014
Record last verified: 2017-02