NCT01324765

Brief Summary

The goal of the study is to evaluate the efficacy of a two therapeutic models designed to enhance women's skills for managing reactive emotions in their current lives as well as to educate them about how using these skills can enhance their personal effectiveness and help them to gain control of post-traumatic stress reactions. The interventions adaptations of a manualized psychotherapy that has shown promise with adults with complex Posttraumatic Stress Disorder (PTSD) (Trauma Affect Regulation: Guide for Education and Therapy; TARGET) compared to a supportive group therapy (SGT) that has been found to have modest benefits with women survivors of childhood abuse (Wallis, 2002).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
108

participants targeted

Target at P50-P75 for phase_2

Timeline
Completed

Started Jan 2009

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2009

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

September 23, 2010

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2010

Completed
5 months until next milestone

First Posted

Study publicly available on registry

March 29, 2011

Completed
Last Updated

March 29, 2011

Status Verified

March 1, 2011

Enrollment Period

1.8 years

First QC Date

September 23, 2010

Last Update Submit

March 28, 2011

Conditions

Keywords

WomenPTSDGroup TherapyIncarceration

Outcome Measures

Primary Outcomes (2)

  • PTSD

    PTSD symptom severity, Clinician Administered PTSD Scale

    Post-therapy (within 2 weeks)

  • PTSD

    PTSD symptom severity, Clinician Administered PTSD Scale

    3-4 Month Post-therapy Follow-up

Secondary Outcomes (6)

  • Emotion Regulation

    Post-therapy (within 2 weeks)

  • Trauma-related symptoms

    Post-therapy (within 2 weeks)

  • Mental health symptoms, well-being, and self-harm

    Post-therapy (within 2 weeks)

  • Emotion Regulation

    3-4 Month Post-therapy Follow-up

  • Trauma-related Symptoms

    3-4 Month Post-therapy Follow-up

  • +1 more secondary outcomes

Study Arms (2)

TARGET

EXPERIMENTAL

12-session affect regulation therapy for PTSD

Behavioral: TARGET

SGT

ACTIVE COMPARATOR

12 session supportive group therapy

Behavioral: SGT

Interventions

TARGETBEHAVIORAL

12-session group therapy twice weekly 6 weeks

TARGET
SGTBEHAVIORAL

12 sessions supportive group therapy twice weekly 6 weeks

SGT

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Incarcerated, release not expected within 6 months
  • Probable PTSD on PC-PTSD screen and PTSD by CAPS interview

You may not qualify if:

  • Clinically significant psychopathy (PCL-SV severe range)
  • Unable to comprehend study materials (Mini-Mental Status Exam Orientation, Attention, and Recall sections total score \<15).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

York Correctional Institution

Niantic, Connecticut, 06357, United States

Location

MeSH Terms

Conditions

Stress Disorders, Post-Traumatic

Condition Hierarchy (Ancestors)

Stress Disorders, TraumaticTrauma and Stressor Related DisordersMental Disorders

Study Officials

  • Julian D Ford, Ph.D.

    UConn Health

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 2
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER

Study Record Dates

First Submitted

September 23, 2010

First Posted

March 29, 2011

Study Start

January 1, 2009

Primary Completion

November 1, 2010

Study Completion

November 1, 2010

Last Updated

March 29, 2011

Record last verified: 2011-03

Locations