Development of 3T Magnetic Resonance Research Methods for NIA Studies

NCT01324206 | Recruiting

• 2 other identifiers: 08023808-AG-0238
• Study Type: observational
• Target: 1,000
• Locations: 1 country
• Sites: 1

Brief Summary

Background: \- Magnetic resonance imaging (MRI) studies provide important information on the structure and function of various body systems, including the brain, muscles, joints, heart, and blood vessels. Scientific applications of MRI scans often use techniques that need to be modified or refined before they are used in clinical studies. To develop and modify these techniques for the new Philips 3T Achieva whole-body MRI scanner, researchers are interested in conducting trial MRI scans on healthy individuals and individuals with conditions that require imaging studies. Objectives: \- To conduct preliminary trials of the 3T MRI facility to develop and refine MRI scanning procedures. Eligibility: \- Individuals at least 18 years of age who are able to have magnetic resonance imaging. Design:

• Participants will be screened with a full medical history and physical examination, as well as blood and urine tests.
• Participants will have an MRI scan using the 3T scanner. Some scans may require the use of a contrast agent or radiotracer, which is a small amount of radioactive substance that will be injected before the start of the scan. Some participants may be asked to perform tasks of thinking and movement while in the scanner, in order to test the procedures required for a functional MRI scan.
• No treatment will be provided as part of this protocol.

Conditions

Normal Physiology

Keywords

Magnetic Resonance Imaging; Healthy Volunteers; Natural History

Outcome Measures

Primary Outcomes (1)

• Develop and refine scanning procedures

  To develop and refine specific imaging and spectroscopic methods.

  2 months

Study Arms (1)

Healthy Volunteers

Healthy Volunteers, 18 or older years

Eligibility Criteria

• Age: 18 Years - 99 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Healthy volunteers, male and female, 18yrs and older

You may qualify if:

• To be eligible to participate in this study, an individual must meet all the following criteria:
• Ability of subject to understand the study and stated willingness to comply with all study procedures.
• Male or female, age \> 18years.
• Able to speak and read English.
• Capable of providing informed consent.
• Subjects or persons identified by an investigator to have a condition of interest for exploratory studies as it relates to aging. These participants are not being scanned for diagnostic purposes.

You may not qualify if:

• An individual who meets any of the following criteria will be excluded from participation in this study:
• Has condition and/or non-removable device contraindicated for MRI as per the MRI eligibility form.
• Weight \> 300lbs (MRI scanner weight limit)
• Is currently pregnant or a nursing mother.

Sponsors & Collaborators

• National Institute on Aging (NIA): lead

Study Sites (1)

National Institute of Aging, Clinical Research Unit

Baltimore, Maryland, 21224, United States

RECRUITING

Related Links

• NIH Clinical Center Detailed Web Page

Study Officials

• Mustapha Bouhrara, Ph.D.

  National Institute on Aging (NIA)

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Seung-Ho Park, R.N.

CONTACT

(410) 350-7315; sarah.park@nih.gov

Mustapha Bouhrara, Ph.D.

CONTACT

(410) 558-8541; bouhraram@mail.nih.gov

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: NIH
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 25, 2011
• First Posted: March 28, 2011
• Study Start: November 3, 2008
• Last Updated: June 1, 2026

Record last verified: 2026-01-08

Locations

US (1)