NCT01319513|Completed
Post-exercise Dietary Protein Strategies
The Effect of the Pattern Post-exercise Aminoacidemia on Myofibrillar Protein Synthesis
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The Effect of the Pattern Post-exercise Aminoacidemia on Myofibrillar Protein Synthesis
Sponsor study identifier
interventional
8
1 country
1
Study Start
July 2009
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
October 2009
Actual (reported)Study Completion
October 2009
Actual (reported)Protein ingestion increases the rate at which the body builds new proteins in skeletal muscle (muscle protein synthesis. This study is designed to examine how the pattern of feeding affects muscle protein synthesis following resistance exercise. There is reason to believe that the large rapid increase in blood amino acid concentrations that accompanies the ingestion of a bolus of protein is important to increasing muscle protein synthesis. Thus, we hypothesize that the consumption a bolus of protein will elevate muscle protein synthesis to a greater extent than the consumption of an equivalent amount of protein that is consumed in small divided doses.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
October 2009
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
July 2009
Date type not reportedThis date has not been verified as actual or estimated.
October 2009
Actual (reported)October 2009
Actual (reported)March 18, 2011
Actual (reported)March 21, 2011
Actual (reported)Rate of myofibrillar protein synthesis
Rates of myofibrillar protein synthesis will be measured from muscle biopsy samples obtained from subjects participating in the study protocol.
4 months
Myocellular protein phosphorylation
4 months
Participants will complete 2 trials in a cross-over fashion in which they will consume whey protein either as a single bolus or as 10 small divided doses
single dose of 25 g whey protein
10 2.5 g pulses of whey protein
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Ivor Wynne Centre A103, McMaster University
Hamilton, Ontario, L8S 4K1, Canada
West DW, Burd NA, Coffey VG, Baker SK, Burke LM, Hawley JA, Moore DR, Stellingwerff T, Phillips SM. Rapid aminoacidemia enhances myofibrillar protein synthesis and anabolic intramuscular signaling responses after resistance exercise. Am J Clin Nutr. 2011 Sep;94(3):795-803. doi: 10.3945/ajcn.111.013722. Epub 2011 Jul 27.
Stuart M Phillips, PhD
McMaster University
8 participants (actual enrollment reported by the registry).
First Submitted
March 18, 2011
First Posted
March 21, 2011
Study Start
July 2009
Date type not reportedThis date has not been verified as actual or estimated.
Contact the study team to confirm eligibility.
Primary Completion
October 2009
Actual (reported)Study Completion
October 2009
Actual (reported)Last Updated
March 21, 2011
Record last verified: 2011-03
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Source: ClinicalTrials.gov.
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