NCT01319032

Brief Summary

In a study conducted in our laboratory few years ago, we genotyped 22 genes in 2 athletic groups (endurance and sprinters) and in age and gender matched nonathletic controls. Few of these genes were found to be associated with athletic performance and area of specificity. Since then a few more genes have been found that are related to athletic performance, and we intend to study various genes related to 3 genetic cascade: genes associated with body fluid balance and homeostasis, genes associated with muscle strength, and genes associated with bioenergy. The results of this study compared with athletic level will provide deeper insight into the genetic mechanisms involved in performance.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Apr 2011

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 17, 2011

Completed
4 days until next milestone

First Posted

Study publicly available on registry

March 21, 2011

Completed
11 days until next milestone

Study Start

First participant enrolled

April 1, 2011

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2011

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2012

Completed
Last Updated

March 21, 2011

Status Verified

March 1, 2011

Enrollment Period

8 months

First QC Date

March 17, 2011

Last Update Submit

March 17, 2011

Conditions

Outcome Measures

Primary Outcomes (1)

  • Identification of genes associated with swimming performance

    One year

Study Arms (2)

I. Top-level swimmers

Other: Extraction of whole blood

II. Control

Other swimmers

Other: Extraction of whole blood

Interventions

Extraction of DNA from whole blood

I. Top-level swimmersII. Control

Eligibility Criteria

Age13 Years - 40 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodProbability Sample
Study Population

Swimmers training at the Wingate Institute

You may qualify if:

  • Top-level swimmers
  • Other swimmers

You may not qualify if:

  • All others

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Wingate Institute

Netanya, Israel

Location

Related Publications (1)

  • Ben-Zaken S, Eliakim A, Nemet D, Rabinovich M, Kassem E, Meckel Y. ACTN3 Polymorphism: Comparison Between Elite Swimmers and Runners. Sports Med Open. 2015;1(1):13. doi: 10.1186/s40798-015-0023-y. Epub 2015 Jun 14.

Biospecimen

Retention: SAMPLES WITH DNA

Whole blood

Central Study Contacts

Sigal Ben Zaken, PhD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER GOV

Study Record Dates

First Submitted

March 17, 2011

First Posted

March 21, 2011

Study Start

April 1, 2011

Primary Completion

December 1, 2011

Study Completion

December 1, 2012

Last Updated

March 21, 2011

Record last verified: 2011-03

Locations