NCT01307280

Brief Summary

The study investigated the effectiveness and cost-effectiveness of a cognitive and behavioral weight management program, complemented by an interactive Web site and brief telephone coaching, implemented among TRICARE non-active-duty beneficiaries. A total of 1,755 participants from four Midwestern states were randomized to one of three randomized controlled trial groups with increasing intervention intensity: mailed material and basic Web access (RCT1), plus an interactive Web site (RCT2), plus brief phone- and Web-based coaching support from health lifestyle coaches (RCT3). The study assessed changes in participants' weight, blood pressure, diet, and physical activity from baseline to 6, 12, and 15 to 18 months. Analyses estimated overall cost savings and calculated the cost-effectiveness ratio of each randomized controlled trial compared with a "do-nothing" alternative as the cost per quality-adjusted life year.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,395

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Aug 2006

Longer than P75 for not_applicable

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2006

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2008

Completed
1.3 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2009

Completed
1.2 years until next milestone

First Submitted

Initial submission to the registry

February 22, 2011

Completed
8 days until next milestone

First Posted

Study publicly available on registry

March 2, 2011

Completed
Last Updated

January 26, 2012

Status Verified

January 1, 2012

Enrollment Period

2 years

First QC Date

February 22, 2011

Last Update Submit

January 25, 2012

Conditions

Keywords

Behavioral Weight Management Interventionweight losscost-effective analysishigh blood pressurerandomized clinical trialbehavioral interventionsphysical activitydietary changeobesity

Outcome Measures

Primary Outcomes (4)

  • Body Mass Index BMI

    change in body mass index at baseline

  • BMI

    change in body mass index at 6 months

  • BMI

    change in body mass index at 12 months

  • BMI

    change in body mass index at 18 months

Secondary Outcomes (1)

  • Blood Pressure

    change in blood pressure at baseline, and 6,12,18 months

Study Arms (3)

Basic HEALTH

EXPERIMENTAL

Participants received the bookHEALTH manual and eHEALTH tools, the basic Internet component of the intervention

Behavioral: RCT1

Interactive Internet

EXPERIMENTAL

Intervention intensity increased in RCT2, which included bookHEALTH and an interactive version of eHEALTH that provided tailored computerized feedback whenever participants submitted weekly assessments.

Behavioral: RCT2

Behavioral Counseling

EXPERIMENTAL

RCT3 included bookHEALTH, the interactive version of eHEALTH, and telephonic coaching support provided by trained health lifestyle coaches every 2 weeks alternating between a telephone call (typically 15 to 20 minutes) and a personalized e-mail. The coaches used motivational interviewing, helped participants solve problems, and reinforced their successes.

Behavioral: RCT3

Interventions

RCT1BEHAVIORAL

the bookHEALTH manual and eHEALTH tools, the basic Internet component of the intervention

Basic HEALTH
RCT2BEHAVIORAL

bookHEALTH and an interactive version of eHEALTH that provided tailored computerized feedback whenever participants submitted weekly assessments

Interactive Internet
RCT3BEHAVIORAL

bookHEALTH, the interactive version of eHEALTH, and telephonic coaching support provided by trained health lifestyle coaches every 2 weeks alternating between a telephone call (typically 15 to 20 minutes) and a personalized e-mail. The coaches used motivational interviewing, helped participants solve problems, and reinforced their successes.

Behavioral Counseling

Eligibility Criteria

Age18 Years - 64 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64)

You may qualify if:

  • TRICARE Prime non-active-duty beneficiaries
  • Body Mass Index of 25 to 50
  • Living in 4 midwestern states (TRICARE region)

You may not qualify if:

  • Not able to engage in physical activity
  • Pregnant
  • Body mass index greater than 50
  • Body mass index less than 25
  • Human immunodeficiency virus infected
  • current cancer

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

RTI Study Center

Swansea, Illinois, 62226, United States

Location

RTI International

Research Triangle Park, North Carolina, 27709, United States

Location

RTI Study Center

Fairborn, Ohio, 45324, United States

Location

Related Publications (1)

  • Hersey JC, Khavjou O, Strange LB, Atkinson RL, Blair SN, Campbell S, Hobbs CL, Kelly B, Fitzgerald TM, Kish-Doto J, Koch MA, Munoz B, Peele E, Stockdale J, Augustine C, Mitchell G, Arday D, Kugler J, Dorn P, Ellzy J, Julian R, Grissom J, Britt M. The efficacy and cost-effectiveness of a community weight management intervention: a randomized controlled trial of the health weight management demonstration. Prev Med. 2012 Jan;54(1):42-9. doi: 10.1016/j.ypmed.2011.09.018. Epub 2011 Oct 6.

MeSH Terms

Conditions

Weight LossHypertensionMotor ActivityObesity

Condition Hierarchy (Ancestors)

Body Weight ChangesBody WeightSigns and SymptomsPathological Conditions, Signs and SymptomsVascular DiseasesCardiovascular DiseasesBehaviorOverweightOvernutritionNutrition DisordersNutritional and Metabolic Diseases

Study Officials

  • James Hersey, PhD

    RTI International

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 22, 2011

First Posted

March 2, 2011

Study Start

August 1, 2006

Primary Completion

August 1, 2008

Study Completion

December 1, 2009

Last Updated

January 26, 2012

Record last verified: 2012-01

Locations