NCT01306864

Brief Summary

The objective of this study is to show that Hemospray is effective in achieving initial hemostasis and documenting rate of further bleed when compared to standard of care.

Trial Health

90
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
67

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Dec 2011

Longer than P75 for not_applicable

Geographic Reach
4 countries

12 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 17, 2011

Completed
13 days until next milestone

First Posted

Study publicly available on registry

March 2, 2011

Completed
9 months until next milestone

Study Start

First participant enrolled

December 1, 2011

Completed
5.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 30, 2017

Completed
29 days until next milestone

Study Completion

Last participant's last visit for all outcomes

May 29, 2017

Completed
Last Updated

February 5, 2018

Status Verified

February 1, 2018

Enrollment Period

5.4 years

First QC Date

February 17, 2011

Last Update Submit

February 1, 2018

Conditions

Keywords

Endoscopic HemostasisPeptic UlcerRecurrent BleedingInjection TherapyThermal Probe

Outcome Measures

Primary Outcomes (1)

  • Proportion of patients with further bleed

    72 Hours

Secondary Outcomes (1)

  • Proportion of patients with initial hemostasis

    At the conclusion of the index procedure

Study Arms (1)

Hemospray Treatment

EXPERIMENTAL

Hemospray Kit

Device: Hemospray Kit

Interventions

Hemostasis of Arterial GI Bleeding

Also known as: Endoscopic Hemostasis
Hemospray Treatment

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Bleeding peptic ulcer

You may not qualify if:

  • Patient is: \< 18 years of age
  • Patient is unable to consent
  • Patient is contraindicated to undergo endoscopy
  • Patient has: coagulopathy, altered post surgical anatomy of the stomach, previously placed intrahepatic portosystemic shunt
  • Patient is pregnant or lactating
  • Patinet has an INR \> 2.5

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (12)

Royal Alexandra

Edmonton, Alberta, TSH 4B9, Canada

Location

Vancouver Coastal Health

Vancouver, British Columbia, Canada

Location

Health Science Centre University of Manitoba

Winnipeg, Manitoba, R3A 1R9, Canada

Location

Queen Elizabeth II Health Sciences Centre

Halifax, Nova Scotia, B3H 2Y9, Canada

Location

London Health Sciences Center

London, Ontario, N6A 4G5, Canada

Location

The Ottawa Hospital- Civic Campus and General Campus

Ottawa, Ontario, K1Y 4E9, Canada

Location

McGill University Health Center

Montreal, Quebec, H3G 1A4, Canada

Location

Prince of Wales Hospital

Hong Kong, Hong Kong

Location

Erasmus MC University Medical Center

Rotterdam, 3015 CE, Netherlands

Location

Belfast City Hospital

Belfast, BT9 7AB, United Kingdom

Location

Bradford Teaching Hospital NHS Foundation

Bradford, BD96RJ, United Kingdom

Location

University of Nottingham

Nottingham, NG 2UH, United Kingdom

Location

Related Publications (1)

  • Sung JJY, Moreea S, Dhaliwal H, Moffatt DC, Ragunath K, Ponich T, Barkun AN, Kuipers EJ, Bailey R, Donnellan F, Wagner D, Sanborn K, Lau J. Use of topical mineral powder as monotherapy for treatment of active peptic ulcer bleeding. Gastrointest Endosc. 2022 Jul;96(1):28-35.e1. doi: 10.1016/j.gie.2022.01.020. Epub 2022 Feb 3.

MeSH Terms

Conditions

Peptic UlcerHemorrhage

Interventions

Hemostasis, Endoscopic

Condition Hierarchy (Ancestors)

Duodenal DiseasesIntestinal DiseasesGastrointestinal DiseasesDigestive System DiseasesStomach DiseasesPathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Hemostatic TechniquesTherapeutics

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 17, 2011

First Posted

March 2, 2011

Study Start

December 1, 2011

Primary Completion

April 30, 2017

Study Completion

May 29, 2017

Last Updated

February 5, 2018

Record last verified: 2018-02

Locations