Oral Rehydration Therapy With 10% Carbohydrate Drink for Preventing Postoperative Nausea and Vomiting (PONV) After Low Dose of Spinal Morphine in Patients Undergoing Total Knee Replacement
Sponsor study identifier
interventional
120
1 country
1
Study Start
February 2011
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
June 2012
Actual (reported)Study Completion
June 2012
Actual (reported)PONV after intrathecal morphine, occurs up to 30-40 percent. The patients having TKR normally are female, obese and non-smoker which are risk factors for PONV. Recently, a multimodal approach, combining several means to minimize PONV, has found wide acceptance as a standard of care. In our hospital, most of the patients are supposed to fast after midnight The oral rehydration therapy reduce patients thirst and increase his satisfaction, but whether or not this method can reduce the incidence of PONV after low dose (0.2 mg) intrathecal morphine is not investigated yet. The aim of this study is to investigate the effect of preoperative oral rehydration therapy on the incidence of PONV.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
June 2012
Actual (reported)Click on a node to explore related trials.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
February 2011
Date type not reportedThis date has not been verified as actual or estimated.
February 20, 2011
Actual (reported)February 23, 2011
Actual (reported)June 2012
Actual (reported)June 2012
Actual (reported)The incidence of postoperative nausea and vomiting after TKR
Compare the incidence, severity and rescue therapy of PONV in control (fast)group a group and the study (carbohydrate drink) group
24 hours
Incidence of hyperglycemia during perioperative period
24 hours
patient receive nothing
10%carbohydrate drink
In the study group, 10% carbohydrate drink 400 ml will be given between 18-24 hr the night before surgery and another 400 ml will be drunk at 6-7 hr in the morning of surgery.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Siriraj Hospital
Bangkok, 10700, Thailand
Manee Raksakietisak, MD
Mahidol University
120 participants (actual enrollment reported by the registry).
First Submitted
February 20, 2011
First Posted
February 23, 2011
Study Start
February 2011
Date type not reportedThis date has not been verified as actual or estimated.
Risk Factors for Postoperative Nausea/Vomiting
Dose-ranging Study of APD405 in Post-operative Nausea and Vomiting (PONV)
Contact the study team to confirm eligibility.
Primary Completion
June 2012
Actual (reported)Study Completion
June 2012
Actual (reported)Last Updated
July 19, 2013
Record last verified: 2012-06
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Source: ClinicalTrials.gov.
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