Graft Take and Microbiology in Burns

NCT01301118 | Suspended DMC

• 1 other identifier: Graft take in burns
• Study Type: observational
• Target: 30
• Locations: 0 countries
• Sites: N/A

Brief Summary

SPLIT-THICKNESS SKIN GRAFT TAKE AND MICROBIOLOGICAL EVALUATION IN BURNED PATIENTS INTRODUCTION: Infection is cause of increased morbidity and mortality in burn patients, and its control is a major challenge also for skin graft integration. Wound and soft tissue infection rates are higher than microbiological diagnosis rates. PURPOSE: To evaluate partial skin graft integration in relation to microbiological analysis of wounds in burn patients. METHODS: This project will be a transversal, prospective, analytical, controlled study in humans, conducted in a single center, at Burn Care Unit of Department of Plastic Surgery at Federal University of São Paulo from October, 2010 to October, 2011. Data will be collected to characterize demographic and clinical aspects. Data analysis will be performed using Student's t-test and Friedman analysis of variance.

Conditions

Transplantation Infection; Wound of Skin; Burns; Graft Loss; Infection

Keywords

Transplantation Infection; Wound of skin; Burns; Graft Loss; Infection

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

ACUTE BURNED PATIENTS

You may qualify if:

• Both gender
• More than 18 years of age
• Burned patient
• Inpatient of Burn Center of Federal University of São Paulo
• Upper 5% of TBSA
• Debridement and skin graft indication and procedure realization

You may not qualify if:

• Not interest in participating in research
• Not have debridement or graft indication
• Under 5% of TBSA
• Skin disease
• Clinical disease that contraindication procedure
• Clinical disease that directly interferes with infectious process and wound healing

Sponsors & Collaborators

• Federal University of São Paulo: lead

MeSH Terms

Conditions

Burns; Infections

Condition Hierarchy (Ancestors)

Wounds and Injuries

Study Officials

• ALFREDO GRAGNANI, MD PhD

  UFSaoPaulo

  PRINCIPAL INVESTIGATOR

• LYDIA M FERREIRA, MD Full Prof

  UFSaoPaulo

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associated Professor

Study Record Dates

• First Submitted: February 22, 2011
• First Posted: February 23, 2011
• Study Start: October 1, 2010
• Last Updated: January 10, 2012

Record last verified: 2012-01